Structural, Dynamical, and Energetical Consequences of Rett Syndrome Mutation R133C in MeCP2

Structural, Dynamical, and Energetical Consequences of Rett Syndrome Mutation R133C in MeCP2

Rett Syndrome (RTT) is a progressive neurodevelopmental disease affecting females. RTT is caused by mutations in the MECP2 gene and various amino acid substitutions have been identified clinically in different domains of the multifunctional MeCP2 protein encoded by this gene. The R133C variant in th...

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Bibliographic Details
Main Authors:	Tugba G. Kucukkal, Emil Alexov
Format:	Article
Language:	English
Published:	Hindawi Limited 2015-01-01
Series:	Computational and Mathematical Methods in Medicine
Online Access:	http://dx.doi.org/10.1155/2015/746157

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