Overexpression of extracellular superoxide dismutase protects against brain injury induced by chronic hypoxia.

Overexpression of extracellular superoxide dismutase protects against brain injury induced by chronic hypoxia.

Extracellular superoxide dismutase (EC-SOD) is an isoform of SOD normally found both intra- and extra-cellularly and accounting for most SOD activity in blood vessels. Here we explored the role of EC-SOD in protecting against brain damage induced by chronic hypoxia. EC-SOD Transgenic mice, were expo...

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Bibliographic Details
Main Authors: Nahla Zaghloul, Hardik Patel, Champa Codipilly, Philippe Marambaud, Stephen Dewey, Stephen Frattini, Patricio T Huerta, Mansoor Nasim, Edmund J Miller, Mohamed Ahmed
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4182464?pdf=render

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