ANALYSIS, ISOLATION AND ACTIVATION OF ANTIGEN-SPECIFIC CD4+ AND CD8+ T CELLS BY SOLUBLE MHC-PEPTIDE COMPLEXES

ANALYSIS, ISOLATION AND ACTIVATION OF ANTIGEN-SPECIFIC CD4+ AND CD8+ T CELLS BY SOLUBLE MHC-PEPTIDE COMPLEXES

T cells constitute the core of adaptive cellular immunity and protect higher organisms against pathogen infections and cancer. Monitoring of disease progression as well as prophylactic or therapeutic vaccines and immunotherapies call for conclusive detection, analysis and sorting of antigen-specific...

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Bibliographic Details
Main Authors: Julien eSchmidt, Danijel eDojcinovic, Philippe eGuillaume, Immanuel eLuescher
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-07-01
Series:Frontiers in Immunology
Subjects:
Flow Cytometry
Vaccination
T cells
T cell receptor
coreceptor
MHC I
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00218/full

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