Toxic Epidermal Necrolysis A Diagnostic Dilemma in Puerperium: A Case Report

Toxic epidermal necrolysis is a potentially life threatening dermatologic disorder characterized by widespread erythema, necrosis and bullas, detachment of epidermis and mucous membrane resulting in exfoliation, possible sepsis and even death. This is the first case report in Nepal of toxic epiderm...

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Main Authors: Vidya Mahto, Meena Thapa, Saraswoti Padhye
Format: Article
Language:English
Published: Nepal Medical Association 2019-10-01
Series:Journal of Nepal Medical Association
Subjects:
Online Access:https://www.jnma.com.np/jnma/index.php/jnma/article/view/4638
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spelling doaj-56cb19dcae7e4c849ee05fe6390b8d332020-11-25T02:20:19ZengNepal Medical AssociationJournal of Nepal Medical Association0028-27151815-672X2019-10-015721910.31729/jnma.4638Toxic Epidermal Necrolysis A Diagnostic Dilemma in Puerperium: A Case ReportVidya Mahto 0Meena Thapa1Saraswoti Padhye2 Department of Obstetrics and Gynecology, Kathmandu Medical College and Teaching Hospital, Sinamangal, Kathmandu, Nepal Department of Obstetrics and Gynecology, Kathmandu Medical College and Teaching Hospital, Sinamangal, Kathmandu, Nepal Department of Obstetrics and Gynecology, Kathmandu Medical College and Teaching Hospital, Sinamangal, Kathmandu, Nepal Toxic epidermal necrolysis is a potentially life threatening dermatologic disorder characterized by widespread erythema, necrosis and bullas, detachment of epidermis and mucous membrane resulting in exfoliation, possible sepsis and even death. This is the first case report in Nepal of toxic epidermal necrolysis in puerperium. We present a case of a 28-years-old, P1L1 on fourth postoperative day following emergency lower segment caesarean section for cephalopelvic disproportion in latent phase of labour with uneventful antenatal period. She developed fever followed by rashes all over the body with hypotension, tachypnea and shortness of breath. Initially, she was diagnosed as a case of septic shock and transferred to intensive care unit from postnatal ward. She was managed with broad spectrum antibiotics and inotropes. Later on, it was found to be the case of Toxic epidermal necrolysis and managed with vancomycin and corticosteroids under the supervision of gynecology, dermatology and medicine team. https://www.jnma.com.np/jnma/index.php/jnma/article/view/4638puerperium; toxic epidermal necrolysis; vancomycin.
collection DOAJ
language English
format Article
sources DOAJ
author Vidya Mahto
Meena Thapa
Saraswoti Padhye
spellingShingle Vidya Mahto
Meena Thapa
Saraswoti Padhye
Toxic Epidermal Necrolysis A Diagnostic Dilemma in Puerperium: A Case Report
Journal of Nepal Medical Association
puerperium; toxic epidermal necrolysis; vancomycin.
author_facet Vidya Mahto
Meena Thapa
Saraswoti Padhye
author_sort Vidya Mahto
title Toxic Epidermal Necrolysis A Diagnostic Dilemma in Puerperium: A Case Report
title_short Toxic Epidermal Necrolysis A Diagnostic Dilemma in Puerperium: A Case Report
title_full Toxic Epidermal Necrolysis A Diagnostic Dilemma in Puerperium: A Case Report
title_fullStr Toxic Epidermal Necrolysis A Diagnostic Dilemma in Puerperium: A Case Report
title_full_unstemmed Toxic Epidermal Necrolysis A Diagnostic Dilemma in Puerperium: A Case Report
title_sort toxic epidermal necrolysis a diagnostic dilemma in puerperium: a case report
publisher Nepal Medical Association
series Journal of Nepal Medical Association
issn 0028-2715
1815-672X
publishDate 2019-10-01
description Toxic epidermal necrolysis is a potentially life threatening dermatologic disorder characterized by widespread erythema, necrosis and bullas, detachment of epidermis and mucous membrane resulting in exfoliation, possible sepsis and even death. This is the first case report in Nepal of toxic epidermal necrolysis in puerperium. We present a case of a 28-years-old, P1L1 on fourth postoperative day following emergency lower segment caesarean section for cephalopelvic disproportion in latent phase of labour with uneventful antenatal period. She developed fever followed by rashes all over the body with hypotension, tachypnea and shortness of breath. Initially, she was diagnosed as a case of septic shock and transferred to intensive care unit from postnatal ward. She was managed with broad spectrum antibiotics and inotropes. Later on, it was found to be the case of Toxic epidermal necrolysis and managed with vancomycin and corticosteroids under the supervision of gynecology, dermatology and medicine team.
topic puerperium; toxic epidermal necrolysis; vancomycin.
url https://www.jnma.com.np/jnma/index.php/jnma/article/view/4638
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AT meenathapa toxicepidermalnecrolysisadiagnosticdilemmainpuerperiumacasereport
AT saraswotipadhye toxicepidermalnecrolysisadiagnosticdilemmainpuerperiumacasereport
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