Adenoviral Vectors Meet Gene Editing: A Rising Partnership for the Genomic Engineering of Human Stem Cells and Their Progeny

Adenoviral Vectors Meet Gene Editing: A Rising Partnership for the Genomic Engineering of Human Stem Cells and Their Progeny

Gene editing permits changing specific DNA sequences within the vast genomes of human cells. Stem cells are particularly attractive targets for gene editing interventions as their self-renewal and differentiation capabilities consent studying cellular differentiation processes, screening small-molec...

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Bibliographic Details
Main Authors: Francesca Tasca, Qian Wang, Manuel A.F.V. Gonçalves
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cells
Subjects:
genome editing
stem cells
induced pluripotent stem cells
programmable nucleases
CRISPR nucleases
adenoviral vectors
Online Access:https://www.mdpi.com/2073-4409/9/4/953

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