The CAGE–MiR-181b-5p–S1PR1 Axis Regulates Anticancer Drug Resistance and Autophagy in Gastric Cancer Cells

The CAGE–MiR-181b-5p–S1PR1 Axis Regulates Anticancer Drug Resistance and Autophagy in Gastric Cancer Cells

Cancer-associated gene (CAGE), a cancer/testis antigen, has been known to promote anticancer drug resistance. Since the underlying mechanisms of CAGE-promoted anticancer drug resistance are poorly understood, we established Anticancer drug-resistant gastric cancer cells (AGSR) to better elucidate po...

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Bibliographic Details
Main Authors: Minjeong Yeon, Youngmi Kim, Deepak Pathak, Eunju Kwon, Dong Young Kim, Myeong Seon Jeong, Hyun Suk Jung, Dooil Jeoung
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
anticancer drug resistance
autophagic flux
cancer-associated gene
miR-181b-5p
sphingosine 1-phosphate receptor
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.666387/full

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