Lewis acid-catalyzed asymmetric reactions of β,γ-unsaturated 2-acyl imidazoles

The investigation of reactivity of β,γ-unsaturated carbonyl compounds is of great synthetic value, especially in asymmetric transformations. Here, the authors report a catalytic asymmetric tandem isomerization/α-Michael addition of β,γ-unsaturated 2-acyl imidazoles in presence of chiral N,N′-dioxide...

Full description

Bibliographic Details
Main Authors:	Tengfei Kang, Liuzhen Hou, Sai Ruan, Weidi Cao, Xiaohua Liu, Xiaoming Feng
Format:	Article
Language:	English
Published:	Nature Publishing Group 2020-08-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-020-17681-9

id	doaj-56eef85e6c18451bb5c7eefe77199ce3
record_format	Article
spelling	doaj-56eef85e6c18451bb5c7eefe77199ce32021-08-08T11:39:20ZengNature Publishing GroupNature Communications2041-17232020-08-0111111010.1038/s41467-020-17681-9Lewis acid-catalyzed asymmetric reactions of β,γ-unsaturated 2-acyl imidazolesTengfei Kang0Liuzhen Hou1Sai Ruan2Weidi Cao3Xiaohua Liu4Xiaoming Feng5Key Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan UniversityKey Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan UniversityKey Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan UniversityKey Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan UniversityKey Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan UniversityKey Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan UniversityThe investigation of reactivity of β,γ-unsaturated carbonyl compounds is of great synthetic value, especially in asymmetric transformations. Here, the authors report a catalytic asymmetric tandem isomerization/α-Michael addition of β,γ-unsaturated 2-acyl imidazoles in presence of chiral N,N′-dioxide metal catalysts.https://doi.org/10.1038/s41467-020-17681-9
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Tengfei Kang Liuzhen Hou Sai Ruan Weidi Cao Xiaohua Liu Xiaoming Feng
spellingShingle	Tengfei Kang Liuzhen Hou Sai Ruan Weidi Cao Xiaohua Liu Xiaoming Feng Lewis acid-catalyzed asymmetric reactions of β,γ-unsaturated 2-acyl imidazoles Nature Communications
author_facet	Tengfei Kang Liuzhen Hou Sai Ruan Weidi Cao Xiaohua Liu Xiaoming Feng
author_sort	Tengfei Kang
title	Lewis acid-catalyzed asymmetric reactions of β,γ-unsaturated 2-acyl imidazoles
title_short	Lewis acid-catalyzed asymmetric reactions of β,γ-unsaturated 2-acyl imidazoles
title_full	Lewis acid-catalyzed asymmetric reactions of β,γ-unsaturated 2-acyl imidazoles
title_fullStr	Lewis acid-catalyzed asymmetric reactions of β,γ-unsaturated 2-acyl imidazoles
title_full_unstemmed	Lewis acid-catalyzed asymmetric reactions of β,γ-unsaturated 2-acyl imidazoles
title_sort	lewis acid-catalyzed asymmetric reactions of β,γ-unsaturated 2-acyl imidazoles
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2020-08-01
description	The investigation of reactivity of β,γ-unsaturated carbonyl compounds is of great synthetic value, especially in asymmetric transformations. Here, the authors report a catalytic asymmetric tandem isomerization/α-Michael addition of β,γ-unsaturated 2-acyl imidazoles in presence of chiral N,N′-dioxide metal catalysts.
url	https://doi.org/10.1038/s41467-020-17681-9
work_keys_str_mv	AT tengfeikang lewisacidcatalyzedasymmetricreactionsofbgunsaturated2acylimidazoles AT liuzhenhou lewisacidcatalyzedasymmetricreactionsofbgunsaturated2acylimidazoles AT sairuan lewisacidcatalyzedasymmetricreactionsofbgunsaturated2acylimidazoles AT weidicao lewisacidcatalyzedasymmetricreactionsofbgunsaturated2acylimidazoles AT xiaohualiu lewisacidcatalyzedasymmetricreactionsofbgunsaturated2acylimidazoles AT xiaomingfeng lewisacidcatalyzedasymmetricreactionsofbgunsaturated2acylimidazoles
_version_	1721215730231279616

Lewis acid-catalyzed asymmetric reactions of β,γ-unsaturated 2-acyl imidazoles

Similar Items