Lewis acid-catalyzed asymmetric reactions of β,γ-unsaturated 2-acyl imidazoles
The investigation of reactivity of β,γ-unsaturated carbonyl compounds is of great synthetic value, especially in asymmetric transformations. Here, the authors report a catalytic asymmetric tandem isomerization/α-Michael addition of β,γ-unsaturated 2-acyl imidazoles in presence of chiral N,N′-dioxide...
Main Authors: | Tengfei Kang, Liuzhen Hou, Sai Ruan, Weidi Cao, Xiaohua Liu, Xiaoming Feng |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2020-08-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-17681-9 |
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