Atypical complication in acute promyelocytic leukemia

Atypical complication in acute promyelocytic leukemia

Acute promyelocytic leukemia (APL) is a distinct subtype of acute myeloid leukemia (AML) with a generally good prognosis but characterized by potentially severe hemorrhagic complications due to coagulopathy, and thus possibly high early mortality. We present the case of a young patient with APL, wit...

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Main Authors: Minodora Onisai, Ana-Maria Vladareanu, Iuliana Iordan, Andreea Spinu, Ana-Maria Neagu, Adrian Alexandru
Format: Article
Language:English
Published: Amaltea Medical Publishing House 2020-12-01
Series:Romanian Medical Journal
Subjects:
acute promyelocytic leukemia
coagulopathy
infections
surgical resection
Online Access:https://rmj.com.ro/articles/2020.4/RMJ_2020_4_Art-16.pdf
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spelling doaj-571d296f4d4a463997d88662a8cc2f412021-09-02T21:28:06ZengAmaltea Medical Publishing HouseRomanian Medical Journal1220-54782069-606X2020-12-0167442542810.37897/RMJ.2020.4.16Atypical complication in acute promyelocytic leukemiaMinodora Onisai0Ana-Maria Vladareanu1Iuliana Iordan2Andreea Spinu3Ana-Maria Neagu4Adrian Alexandru5„Carol Davila“ University of Medicine and Pharmacy, Bucharest, Romania; Hematology Department, Emergency University Hospital, Bucharest, Romania„Carol Davila“ University of Medicine and Pharmacy, Bucharest, Romania; Hematology Department, Emergency University Hospital, Bucharest, Romania„Carol Davila“ University of Medicine and Pharmacy, Bucharest, Romania; Hematology Department, Emergency University Hospital, Bucharest, Romania„Carol Davila“ University of Medicine and Pharmacy, Bucharest, Romania; Hematology Department, Emergency University Hospital, Bucharest, Romania„Carol Davila“ University of Medicine and Pharmacy, Bucharest, Romania; Hematology Department, Emergency University Hospital, Bucharest, Romania „Carol Davila“ University of Medicine and Pharmacy, Bucharest, Romania 2 Hematology Department, Emergency University Hospital, Bucharest, Romania; Plastic and Reconstructive Surgery Clinic, Emergency University Hospital, Bucharest, RomaniaAcute promyelocytic leukemia (APL) is a distinct subtype of acute myeloid leukemia (AML) with a generally good prognosis but characterized by potentially severe hemorrhagic complications due to coagulopathy, and thus possibly high early mortality. We present the case of a young patient with APL, with a complication which was unresponsive to conservative treatment and required surgical resection, namely herpetic lesion complicated with infection and necrosis. This case sustains the importance of teamwork in hematologic patients. https://rmj.com.ro/articles/2020.4/RMJ_2020_4_Art-16.pdfacute promyelocytic leukemiacoagulopathyinfectionssurgical resection
collection DOAJ
language English
format Article
sources DOAJ
author Minodora Onisai
Ana-Maria Vladareanu
Iuliana Iordan
Andreea Spinu
Ana-Maria Neagu
Adrian Alexandru
spellingShingle Minodora Onisai
Ana-Maria Vladareanu
Iuliana Iordan
Andreea Spinu
Ana-Maria Neagu
Adrian Alexandru
Atypical complication in acute promyelocytic leukemia
Romanian Medical Journal
acute promyelocytic leukemia
coagulopathy
infections
surgical resection
author_facet Minodora Onisai
Ana-Maria Vladareanu
Iuliana Iordan
Andreea Spinu
Ana-Maria Neagu
Adrian Alexandru
author_sort Minodora Onisai
title Atypical complication in acute promyelocytic leukemia
title_short Atypical complication in acute promyelocytic leukemia
title_full Atypical complication in acute promyelocytic leukemia
title_fullStr Atypical complication in acute promyelocytic leukemia
title_full_unstemmed Atypical complication in acute promyelocytic leukemia
title_sort atypical complication in acute promyelocytic leukemia
publisher Amaltea Medical Publishing House
series Romanian Medical Journal
issn 1220-5478
2069-606X
publishDate 2020-12-01
description Acute promyelocytic leukemia (APL) is a distinct subtype of acute myeloid leukemia (AML) with a generally good prognosis but characterized by potentially severe hemorrhagic complications due to coagulopathy, and thus possibly high early mortality. We present the case of a young patient with APL, with a complication which was unresponsive to conservative treatment and required surgical resection, namely herpetic lesion complicated with infection and necrosis. This case sustains the importance of teamwork in hematologic patients.
topic acute promyelocytic leukemia
coagulopathy
infections
surgical resection
url https://rmj.com.ro/articles/2020.4/RMJ_2020_4_Art-16.pdf
work_keys_str_mv AT minodoraonisai atypicalcomplicationinacutepromyelocyticleukemia
AT anamariavladareanu atypicalcomplicationinacutepromyelocyticleukemia
AT iulianaiordan atypicalcomplicationinacutepromyelocyticleukemia
AT andreeaspinu atypicalcomplicationinacutepromyelocyticleukemia
AT anamarianeagu atypicalcomplicationinacutepromyelocyticleukemia
AT adrianalexandru atypicalcomplicationinacutepromyelocyticleukemia
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