PHOTODYNAMIC DIAGNOSIS AND FLUORESCENCE SPECTROSCOPY IN SUPERFICIAL BLADDER CANCER

PHOTODYNAMIC DIAGNOSIS AND FLUORESCENCE SPECTROSCOPY IN SUPERFICIAL BLADDER CANCER

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A comprehensive fluorescence technique has been developed to study the urinary bladder mucosa in patients with superficial bladder cancer (BC), by using alasense, white light cystoscopy, fluorescence cytoscopy, and local fluorescence spectroscopy in vivo. Quantification of urothelium fluorescence in...

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Bibliographic Details
Main Authors: I. G. Rusakov, V. V. Sokolov, N. N. Bulgakova, A. A. Teplov, R. V. Ulyanov
Format: Article
Language:Russian
Published: ABV-press 2014-08-01
Series:Onkourologiâ
Subjects:
bladder cancer
photodynamic diagnosis
fluorescence spectroscopy
alasense
Online Access:https://oncourology.abvpress.ru/oncur/article/view/296
Description
Summary:A comprehensive fluorescence technique has been developed to study the urinary bladder mucosa in patients with superficial bladder cancer (BC), by using alasense, white light cystoscopy, fluorescence cytoscopy, and local fluorescence spectroscopy in vivo. Quantification of urothelium fluorescence in the red emission foci of 5-ALA-induced protophorphyrin, with the local autofluorescence intensity being borne in mind, has been shown to increase the specificity of photodynamic diagnosis of superficial BC from 70 to 85% (p ≤ 0.05) and the total accuracy of the technique from 80 to 86%.
ISSN:1726-9776
1996-1812

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