PHOTODYNAMIC DIAGNOSIS AND FLUORESCENCE SPECTROSCOPY IN SUPERFICIAL BLADDER CANCER

PHOTODYNAMIC DIAGNOSIS AND FLUORESCENCE SPECTROSCOPY IN SUPERFICIAL BLADDER CANCER

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A comprehensive fluorescence technique has been developed to study the urinary bladder mucosa in patients with superficial bladder cancer (BC), by using alasense, white light cystoscopy, fluorescence cytoscopy, and local fluorescence spectroscopy in vivo. Quantification of urothelium fluorescence in...

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Main Authors: I. G. Rusakov, V. V. Sokolov, N. N. Bulgakova, A. A. Teplov, R. V. Ulyanov
Format: Article
Language:Russian
Published: ABV-press 2014-08-01
Series:Onkourologiâ
Subjects:
bladder cancer
photodynamic diagnosis
fluorescence spectroscopy
alasense
Online Access:https://oncourology.abvpress.ru/oncur/article/view/296
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spelling doaj-57468c03f1454185b57384551a6192722021-07-29T08:41:39ZrusABV-pressOnkourologiâ 1726-97761996-18122014-08-0154414610.17650/1726-9776-2009-5-4-41-46311PHOTODYNAMIC DIAGNOSIS AND FLUORESCENCE SPECTROSCOPY IN SUPERFICIAL BLADDER CANCERI. G. Rusakov0V. V. Sokolov1N. N. Bulgakova2A. A. Teplov3R. V. Ulyanov4P.A. Herzen Moscow Research Oncological InstituteP.A. Herzen Moscow Research Oncological InstituteM.A. Prokhorov General Physics Institute, Russian Academy of Science, MoscowP.A. Herzen Moscow Research Oncological InstituteP.A. Herzen Moscow Research Oncological InstituteA comprehensive fluorescence technique has been developed to study the urinary bladder mucosa in patients with superficial bladder cancer (BC), by using alasense, white light cystoscopy, fluorescence cytoscopy, and local fluorescence spectroscopy in vivo. Quantification of urothelium fluorescence in the red emission foci of 5-ALA-induced protophorphyrin, with the local autofluorescence intensity being borne in mind, has been shown to increase the specificity of photodynamic diagnosis of superficial BC from 70 to 85% (p ≤ 0.05) and the total accuracy of the technique from 80 to 86%.https://oncourology.abvpress.ru/oncur/article/view/296bladder cancerphotodynamic diagnosisfluorescence spectroscopyalasense
collection DOAJ
language Russian
format Article
sources DOAJ
author I. G. Rusakov
V. V. Sokolov
N. N. Bulgakova
A. A. Teplov
R. V. Ulyanov
spellingShingle I. G. Rusakov
V. V. Sokolov
N. N. Bulgakova
A. A. Teplov
R. V. Ulyanov
PHOTODYNAMIC DIAGNOSIS AND FLUORESCENCE SPECTROSCOPY IN SUPERFICIAL BLADDER CANCER
Onkourologiâ
bladder cancer
photodynamic diagnosis
fluorescence spectroscopy
alasense
author_facet I. G. Rusakov
V. V. Sokolov
N. N. Bulgakova
A. A. Teplov
R. V. Ulyanov
author_sort I. G. Rusakov
title PHOTODYNAMIC DIAGNOSIS AND FLUORESCENCE SPECTROSCOPY IN SUPERFICIAL BLADDER CANCER
title_short PHOTODYNAMIC DIAGNOSIS AND FLUORESCENCE SPECTROSCOPY IN SUPERFICIAL BLADDER CANCER
title_full PHOTODYNAMIC DIAGNOSIS AND FLUORESCENCE SPECTROSCOPY IN SUPERFICIAL BLADDER CANCER
title_fullStr PHOTODYNAMIC DIAGNOSIS AND FLUORESCENCE SPECTROSCOPY IN SUPERFICIAL BLADDER CANCER
title_full_unstemmed PHOTODYNAMIC DIAGNOSIS AND FLUORESCENCE SPECTROSCOPY IN SUPERFICIAL BLADDER CANCER
title_sort photodynamic diagnosis and fluorescence spectroscopy in superficial bladder cancer
publisher ABV-press
series Onkourologiâ
issn 1726-9776
1996-1812
publishDate 2014-08-01
description A comprehensive fluorescence technique has been developed to study the urinary bladder mucosa in patients with superficial bladder cancer (BC), by using alasense, white light cystoscopy, fluorescence cytoscopy, and local fluorescence spectroscopy in vivo. Quantification of urothelium fluorescence in the red emission foci of 5-ALA-induced protophorphyrin, with the local autofluorescence intensity being borne in mind, has been shown to increase the specificity of photodynamic diagnosis of superficial BC from 70 to 85% (p ≤ 0.05) and the total accuracy of the technique from 80 to 86%.
topic bladder cancer
photodynamic diagnosis
fluorescence spectroscopy
alasense
url https://oncourology.abvpress.ru/oncur/article/view/296
work_keys_str_mv AT igrusakov photodynamicdiagnosisandfluorescencespectroscopyinsuperficialbladdercancer
AT vvsokolov photodynamicdiagnosisandfluorescencespectroscopyinsuperficialbladdercancer
AT nnbulgakova photodynamicdiagnosisandfluorescencespectroscopyinsuperficialbladdercancer
AT aateplov photodynamicdiagnosisandfluorescencespectroscopyinsuperficialbladdercancer
AT rvulyanov photodynamicdiagnosisandfluorescencespectroscopyinsuperficialbladdercancer
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