| Summary: | Background: Histological subtypes of lung carcinoma vary between gender and age groups. Younger age group has more predilections for adenocarcinoma (ACC) while squamous cell carcinoma (SCC) is more common in older age group. Gender wise, ACC is more frequent among females as compare to males. Aim: Present study analysed the distribution of histological subtypes among different age groups (younger vs. older) and gender (male vs. females) to find out predominance of any particular subtype or a specific pattern relating to age and gender in Indian population. Materials and Methods: Data of 342 patients were retrospectively analysed in terms of age, gender and pathological diagnosis. The patients were grouped into two, younger age group (≤50 years) and older age group (>50 years). Results: There were 280 (81.87%) male and 62 (18.12%) female patients. Male:female ratio was 4:51. There were 134 patients (39.18%) in younger age group and 208 (60.81%) patients in older age group. Majority of the patients (272) were nonsmall cell lung carcinoma (NSCLC) (79.53%) while 70 patients had small cell lung carcinoma (20.46%). Out of 272 patients with NSCLC, 130 (38%), were SCC, 92 (26.90%) patients had ACC and rest 50 (14.61%) patients were of large cell lung carcinoma. No significant predilection for a particular histological subtype in younger and older age group was observed. In males SCC was the most common subtype (42.14%, P = 0.0014) and in females ACC was most frequent (48.38%, P = 0.0001). Conclusion: Squamous cell carcinoma in males, ACC in females and overall SCC is the most common histological subtype. No significant correlation with age was found.
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