Pharmacological Insights into Halophyte Bioactive Extract Action on Anti-Inflammatory, Pain Relief and Antibiotics-Type Mechanisms
The pharmacological activities in bioactive plant extracts play an increasing role in sustainable resources for valorization and biomedical applications. Bioactive phytochemicals, including natural compounds, secondary metabolites and their derivatives, have attracted significant attention for use i...
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doaj-577e554925d84c3badbc8590f5617bf12021-06-01T00:58:11ZengMDPI AGMolecules1420-30492021-05-01263140314010.3390/molecules26113140Pharmacological Insights into Halophyte Bioactive Extract Action on Anti-Inflammatory, Pain Relief and Antibiotics-Type MechanismsRocco Giordano0Zeinab Saii1Malthe Fredsgaard2Laura Sini Sofia Hulkko3Thomas Bouet Guldbæk Poulsen4Mikkel Eggert Thomsen5Nanna Henneberg6Silvana Maria Zucolotto7Lars Arendt-Nielsen8Jutta Papenbrock9Mette Hedegaard Thomsen10Allan Stensballe11Department of Health Science and Technology, Aalborg University, 9220 Aalborg, DenmarkDepartment of Health Science and Technology, Aalborg University, 9220 Aalborg, DenmarkDepartment of Energy Technology, Aalborg University, 9220 Aalborg, DenmarkDepartment of Energy Technology, Aalborg University, 9220 Aalborg, DenmarkDepartment of Health Science and Technology, Aalborg University, 9220 Aalborg, DenmarkDepartment of Health Science and Technology, Aalborg University, 9220 Aalborg, DenmarkDepartment of Health Science and Technology, Aalborg University, 9220 Aalborg, DenmarkCenter of Health Sciences, Department of Pharmaceutical Science, Federal University of Santa Catarina, Campus Universitário, Trindade, 88040–970 Florianópolis, BrazilDepartment of Health Science and Technology, Aalborg University, 9220 Aalborg, DenmarkInstitute of Botany, Leibniz University Hannover, D-30419 Hannover, GermanyDepartment of Energy Technology, Aalborg University, 9220 Aalborg, DenmarkDepartment of Health Science and Technology, Aalborg University, 9220 Aalborg, DenmarkThe pharmacological activities in bioactive plant extracts play an increasing role in sustainable resources for valorization and biomedical applications. Bioactive phytochemicals, including natural compounds, secondary metabolites and their derivatives, have attracted significant attention for use in both medicinal products and cosmetic products. Our review highlights the pharmacological mode-of-action and current biomedical applications of key bioactive compounds applied as anti-inflammatory, bactericidal with antibiotics effects, and pain relief purposes in controlled clinical studies or preclinical studies. In this systematic review, the availability of bioactive compounds from several salt-tolerant plant species, mainly focusing on the three promising species <i>Aster tripolium</i>, <i>Crithmum maritimum</i> and <i>Salicornia europaea</i>, are summarized and discussed. All three of them have been widely used in natural folk medicines and are now in the focus for future nutraceutical and pharmacological applications.https://www.mdpi.com/1420-3049/26/11/3140secondary metaboliteshalophyteshydroxycinnamic acidinflammationnutraceuticals |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Rocco Giordano Zeinab Saii Malthe Fredsgaard Laura Sini Sofia Hulkko Thomas Bouet Guldbæk Poulsen Mikkel Eggert Thomsen Nanna Henneberg Silvana Maria Zucolotto Lars Arendt-Nielsen Jutta Papenbrock Mette Hedegaard Thomsen Allan Stensballe |
spellingShingle |
Rocco Giordano Zeinab Saii Malthe Fredsgaard Laura Sini Sofia Hulkko Thomas Bouet Guldbæk Poulsen Mikkel Eggert Thomsen Nanna Henneberg Silvana Maria Zucolotto Lars Arendt-Nielsen Jutta Papenbrock Mette Hedegaard Thomsen Allan Stensballe Pharmacological Insights into Halophyte Bioactive Extract Action on Anti-Inflammatory, Pain Relief and Antibiotics-Type Mechanisms Molecules secondary metabolites halophytes hydroxycinnamic acid inflammation nutraceuticals |
author_facet |
Rocco Giordano Zeinab Saii Malthe Fredsgaard Laura Sini Sofia Hulkko Thomas Bouet Guldbæk Poulsen Mikkel Eggert Thomsen Nanna Henneberg Silvana Maria Zucolotto Lars Arendt-Nielsen Jutta Papenbrock Mette Hedegaard Thomsen Allan Stensballe |
author_sort |
Rocco Giordano |
title |
Pharmacological Insights into Halophyte Bioactive Extract Action on Anti-Inflammatory, Pain Relief and Antibiotics-Type Mechanisms |
title_short |
Pharmacological Insights into Halophyte Bioactive Extract Action on Anti-Inflammatory, Pain Relief and Antibiotics-Type Mechanisms |
title_full |
Pharmacological Insights into Halophyte Bioactive Extract Action on Anti-Inflammatory, Pain Relief and Antibiotics-Type Mechanisms |
title_fullStr |
Pharmacological Insights into Halophyte Bioactive Extract Action on Anti-Inflammatory, Pain Relief and Antibiotics-Type Mechanisms |
title_full_unstemmed |
Pharmacological Insights into Halophyte Bioactive Extract Action on Anti-Inflammatory, Pain Relief and Antibiotics-Type Mechanisms |
title_sort |
pharmacological insights into halophyte bioactive extract action on anti-inflammatory, pain relief and antibiotics-type mechanisms |
publisher |
MDPI AG |
series |
Molecules |
issn |
1420-3049 |
publishDate |
2021-05-01 |
description |
The pharmacological activities in bioactive plant extracts play an increasing role in sustainable resources for valorization and biomedical applications. Bioactive phytochemicals, including natural compounds, secondary metabolites and their derivatives, have attracted significant attention for use in both medicinal products and cosmetic products. Our review highlights the pharmacological mode-of-action and current biomedical applications of key bioactive compounds applied as anti-inflammatory, bactericidal with antibiotics effects, and pain relief purposes in controlled clinical studies or preclinical studies. In this systematic review, the availability of bioactive compounds from several salt-tolerant plant species, mainly focusing on the three promising species <i>Aster tripolium</i>, <i>Crithmum maritimum</i> and <i>Salicornia europaea</i>, are summarized and discussed. All three of them have been widely used in natural folk medicines and are now in the focus for future nutraceutical and pharmacological applications. |
topic |
secondary metabolites halophytes hydroxycinnamic acid inflammation nutraceuticals |
url |
https://www.mdpi.com/1420-3049/26/11/3140 |
work_keys_str_mv |
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