Select small core structure carbamates exhibit high contact toxicity to "carbamate-resistant" strain malaria mosquitoes, Anopheles gambiae (Akron).
Acetylcholinesterase (AChE) is a proven target for control of the malaria mosquito (Anopheles gambiae). Unfortunately, a single amino acid mutation (G119S) in An. gambiae AChE-1 (AgAChE) confers resistance to the AChE inhibitors currently approved by the World Health Organization for indoor residual...
Main Authors: | Dawn M Wong, Jianyong Li, Qiao-Hong Chen, Qian Han, James M Mutunga, Ania Wysinski, Troy D Anderson, Haizhen Ding, Tiffany L Carpenetti, Astha Verma, Rafique Islam, Sally L Paulson, Polo C-H Lam, Maxim Totrov, Jeffrey R Bloomquist, Paul R Carlier |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3462181?pdf=render |
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