Manipulation of microbiota reveals altered callosal myelination and white matter plasticity in a model of Huntington disease
Structural and molecular myelination deficits represent early pathological features of Huntington disease (HD). Recent evidence from germ-free (GF) animals suggests a role for microbiota-gut-brain bidirectional communication in the regulation of myelination. In this study, we aimed to investigate th...
Main Authors: | Carola I. Radulescu, Marta Garcia-Miralles, Harwin Sidik, Costanza Ferrari Bardile, Nur Amirah Binte Mohammad Yusof, Hae Ung Lee, Eliza Xin Pei Ho, Collins Wenhan Chu, Emma Layton, Donovan Low, Paola Florez De Sessions, Sven Pettersson, Florent Ginhoux, Mahmoud A. Pouladi |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-07-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996118305515 |
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