An in vitro study on factors affecting endotoxin neutralization in human plasma using the Limulus amebocyte lysate test

Abstract Endotoxin neutralization, caused by plasma components, makes it difficult to detect endotoxins in human blood. In this study, we investigated which factors influence the recovery of endotoxins using limulus ameobocyte lysate (LAL)-based assays. The individual factors that were examined in m...

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Bibliographic Details
Main Authors: Stephan Harm, Claudia Schildböck, Karin Strobl, Jens Hartmann
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-83487-4