AP-1/KIF13A Blocking Peptides Impair Melanosome Maturation and Melanin Synthesis

AP-1/KIF13A Blocking Peptides Impair Melanosome Maturation and Melanin Synthesis

Melanocytes are specialized cells that generate unique organelles called melanosomes in which melanin is synthesized and stored. Melanosome biogenesis and melanocyte pigmentation require the transport and delivery of melanin synthesizing enzymes, such as tyrosinase and related proteins (e.g., TYRP1)...

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Bibliographic Details
Main Authors: Cécile Campagne, Léa Ripoll, Floriane Gilles-Marsens, Graça Raposo, Cédric Delevoye
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:International Journal of Molecular Sciences
Subjects:
pigmentation
melanocytes
kinesin
adaptor protein
peptide
melanosome biogenesis and maturation
Online Access:http://www.mdpi.com/1422-0067/19/2/568

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