CTLA-4 Polymorphisms in Patients with IgA Nephropathy Correlate with Proteinuria

CTLA-4 Polymorphisms in Patients with IgA Nephropathy Correlate with Proteinuria

Background/Aims: IgA nephropathy (IgAN) is the most common form of primary glomerulonephritis and still constitutes one of the most important causes of end-stage renal disease. Abnormal T cell responses may play a role in IgAN pathogenesis. Co-stimulatory molecules such as cytotoxic T lymphocyte-ass...

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Bibliographic Details
Main Authors: Marius Jacob, Kim Ohl, Tannaz Goodarzi, Sigrid Harendza, Thomas Eggermann, Christina Fitzner, Ralf-Dieter Hilgers, Anna Bolte, Jürgen Floege, Thomas Rauen, Klaus Tenbrock
Format: Article
Language:English
Published: Karger Publishers 2018-03-01
Series:Kidney & Blood Pressure Research
Subjects:
Single nucleotide polymorphism
CTLA-4
IgA nephropathy
IgAN
STOP-IgAN
Online Access:https://www.karger.com/Article/FullText/488069

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