Production, purification, and radiolabeling of the 203Pb/212Pb theranostic pair

Production, purification, and radiolabeling of the 203Pb/212Pb theranostic pair

Abstract Background Lead-212 (212Pb, t1/2 = 10.6 h) and lead-203 (203Pb, t1/2 = 51.9 h) are an element-equivalent, or a matched theranostic radioisotope pair that show great potential for application in targeted radionuclide therapy (TRT) and single-photon emission computed tomography (SPECT), respe...

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Bibliographic Details
Main Authors: Brooke L. McNeil, Andrew K. H. Robertson, Winnie Fu, Hua Yang, Cornelia Hoehr, Caterina F. Ramogida, Paul Schaffer
Format: Article
Language:English
Published: SpringerOpen 2021-02-01
Series:EJNMMI Radiopharmacy and Chemistry
Subjects:
Lead-212
Lead-203
Thorium-228 generator
Thallium-203
Theranostic
Cyclen
Online Access:https://doi.org/10.1186/s41181-021-00121-4

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