Integrin-linked kinase controls retinal angiogenesis and is linked to Wnt signaling and exudative vitreoretinopathy
Integrin-linked kinase (ILK) is an important mediator of integrin signaling. Here Park et al. show that mice with endothelial-specific deletion of Ilk develop vascular defects that resemble familial exudative vitreoretinopathy, and identify mutations in ILK in patients with exudative vitreoretinopat...
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Bibliographic Details
| Main Authors: |
Hongryeol Park,
Hiroyuki Yamamoto,
Lucas Mohn,
Lea Ambühl,
Kenichi Kanai,
Inga Schmidt,
Kee-Pyo Kim,
Alessia Fraccaroli,
Silke Feil,
Harald J. Junge,
Eloi Montanez,
Wolfgang Berger,
Ralf H. Adams |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2019-11-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-019-13220-3
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