Aliskiren, a Direct Renin Inhibitor, Improves Vascular Endothelial Function in Patients on Hemodialysis Independent of Antihypertensive Effect ∼ a Pilot Study∼

Aliskiren, a Direct Renin Inhibitor, Improves Vascular Endothelial Function in Patients on Hemodialysis Independent of Antihypertensive Effect ∼ a Pilot Study∼

Aims: Aliskiren inhibits the first step in the renin-angiotensin system (RAS) and recently has been shown to modulate vascular diseases via RAS-dependent and independent pathways. This study aimed to determine the effect of aliskiren-associated direct renin inhibition on endothelial function in pati...

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Bibliographic Details
Main Authors: Hidekazu Moriya, Shuzo Kobayashi, Takayasu Ohtake, Daimu Tutumi, Yasuhiro Mochida, Kunihiro Ishioka, Machiko Oka, Kyoko Maesato, Sumi Hidaka, Shosaku Nomura
Format: Article
Language:English
Published: Karger Publishers 2013-05-01
Series:Kidney & Blood Pressure Research
Subjects:
Aliskiren
Flow-mediated dilatation
Platelet derived microparticle
Hemodialysis
Blood pressure
Online Access:http://www.karger.com/Article/FullText/350144

Internet

http://www.karger.com/Article/FullText/350144

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