Oxidant production and SOD1 protein expression in single skeletal myofibers from Down syndrome mice
Down syndrome (DS) is a genetic condition caused by the triplication of chromosome 21. Persons with DS exhibit pronounced muscle weakness, which also occurs in the Ts65Dn mouse model of DS. Oxidative stress is thought to be an underlying factor in the development of DS-related pathologies including...
Main Authors: | Patrick M. Cowley, Divya R. Nair, Lara R. DeRuisseau, Stefan Keslacy, Mustafa Atalay, Keith C. DeRuisseau |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2017-10-01
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Series: | Redox Biology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213231717302574 |
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