Multispectral optoacoustic imaging of dynamic redox correlation and pathophysiological progression utilizing upconversion nanoprobes

Reactive oxygen (ROS) and nitrogen (RNS) species are involved in key physiological processes and their balance is altered in various human diseases. Here the authors develop near-infrared upconversion nanoprobes to screen ROS/RNS dynamics simultaneously by multispectral optoacoustic imaging in vivo.

Bibliographic Details
Main Authors: Xiangzhao Ai, Zhimin Wang, Haolun Cheong, Yong Wang, Ruochong Zhang, Jun Lin, Yuanjin Zheng, Mingyuan Gao, Bengang Xing
Format: Article
Language:English
Published: Nature Publishing Group 2019-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-09001-7
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spelling doaj-58f1407ab96d47609f3ce2aae44556492021-05-11T11:38:21ZengNature Publishing GroupNature Communications2041-17232019-03-0110111110.1038/s41467-019-09001-7Multispectral optoacoustic imaging of dynamic redox correlation and pathophysiological progression utilizing upconversion nanoprobesXiangzhao Ai0Zhimin Wang1Haolun Cheong2Yong Wang3Ruochong Zhang4Jun Lin5Yuanjin Zheng6Mingyuan Gao7Bengang Xing8Sino-Singapore International Joint Research Institute (SSIJRI)Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological UniversityDivision of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological UniversityState Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X), Soochow UniversitySchool of Electrical and Electronic Engineering, Nanyang Technological UniversityState Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of SciencesSchool of Electrical and Electronic Engineering, Nanyang Technological UniversityState Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X), Soochow UniversitySino-Singapore International Joint Research Institute (SSIJRI)Reactive oxygen (ROS) and nitrogen (RNS) species are involved in key physiological processes and their balance is altered in various human diseases. Here the authors develop near-infrared upconversion nanoprobes to screen ROS/RNS dynamics simultaneously by multispectral optoacoustic imaging in vivo.https://doi.org/10.1038/s41467-019-09001-7
collection DOAJ
language English
format Article
sources DOAJ
author Xiangzhao Ai
Zhimin Wang
Haolun Cheong
Yong Wang
Ruochong Zhang
Jun Lin
Yuanjin Zheng
Mingyuan Gao
Bengang Xing
spellingShingle Xiangzhao Ai
Zhimin Wang
Haolun Cheong
Yong Wang
Ruochong Zhang
Jun Lin
Yuanjin Zheng
Mingyuan Gao
Bengang Xing
Multispectral optoacoustic imaging of dynamic redox correlation and pathophysiological progression utilizing upconversion nanoprobes
Nature Communications
author_facet Xiangzhao Ai
Zhimin Wang
Haolun Cheong
Yong Wang
Ruochong Zhang
Jun Lin
Yuanjin Zheng
Mingyuan Gao
Bengang Xing
author_sort Xiangzhao Ai
title Multispectral optoacoustic imaging of dynamic redox correlation and pathophysiological progression utilizing upconversion nanoprobes
title_short Multispectral optoacoustic imaging of dynamic redox correlation and pathophysiological progression utilizing upconversion nanoprobes
title_full Multispectral optoacoustic imaging of dynamic redox correlation and pathophysiological progression utilizing upconversion nanoprobes
title_fullStr Multispectral optoacoustic imaging of dynamic redox correlation and pathophysiological progression utilizing upconversion nanoprobes
title_full_unstemmed Multispectral optoacoustic imaging of dynamic redox correlation and pathophysiological progression utilizing upconversion nanoprobes
title_sort multispectral optoacoustic imaging of dynamic redox correlation and pathophysiological progression utilizing upconversion nanoprobes
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2019-03-01
description Reactive oxygen (ROS) and nitrogen (RNS) species are involved in key physiological processes and their balance is altered in various human diseases. Here the authors develop near-infrared upconversion nanoprobes to screen ROS/RNS dynamics simultaneously by multispectral optoacoustic imaging in vivo.
url https://doi.org/10.1038/s41467-019-09001-7
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