The roles of PINK1 and Parkin in Parkinson's disease.

The roles of PINK1 and Parkin in Parkinson's disease.

Bibliographic Details
Main Author:	Rachel Jones
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2010-01-01
Series:	PLoS Biology
Online Access:	http://europepmc.org/articles/PMC2811156?pdf=render

Similar Items

Involvement of PINK1 and Parkin in the pathogenesis of Parkinson's disease
by: Narendra, Derek
Published: (2012)

PINK1/Parkin-Dependent Mitochondrial Surveillance: From Pleiotropy to Parkinson's Disease
by: Olga Corti, et al.
Published: (2017-05-01)

Functional analysis of the Parkinson's disease associated genes, parkin and PINK1, in vitro
by: Muqit, M. M. K.
Published: (2007)

S-Nitrosylation of PINK1 Attenuates PINK1/Parkin-Dependent Mitophagy in hiPSC-Based Parkinson’s Disease Models
by: Chang-Ki Oh, et al.
Published: (2017-11-01)

S-Nitrosylation of PINK1 Attenuates PINK1/Parkin-Dependent Mitophagy in hiPSC-Based Parkinson's Disease Models
by: Oh, Chang-Ki, et al.
Published: (2018)

PINK1 and Parkin mitochondrial quality control: a source of regional vulnerability in Parkinson’s disease
by: Preston Ge, et al.
Published: (2020-03-01)

New perception of mitochondrial regulatory pathway in parkinsonism- ubiquitin, PINK1 and parkin.
by: Diana Angelika Olszewska, et al.
Published: (2014-11-01)

PINK1-mediated phosphorylation of Parkin boosts Parkin activity in Drosophila.
by: Kahori Shiba-Fukushima, et al.
Published: (2014-06-01)

MUL1 acts in parallel to the PINK1/parkin pathway in regulating mitofusin and compensates for loss of PINK1/parkin
by: Jina Yun, et al.
Published: (2014-06-01)

PINK1/PARKIN signalling in neurodegeneration and neuroinflammation
by: Peter M. J. Quinn, et al.
Published: (2020-11-01)

Commentary: Nix restores mitophagy and mitochondrial function to protect against PINK1/Parkin-related Parkinson's disease
by: Jin-Sung Park, et al.
Published: (2017-09-01)

Significance of the <it>parkin </it>and <it>PINK1 </it>gene in Jordanian families with incidences of young-onset and juvenile parkinsonism
by: Nusier Mohamad K, et al.
Published: (2008-12-01)

Exon Dosage Variations in Brazilian Patients with Parkinson’s Disease: Analysis of SNCA, PARKIN, PINK1 and DJ-1 Genes
by: Karla Cristina Vasconcelos Moura, et al.
Published: (2012-01-01)

PINK1-Parkin pathway activity is regulated by degradation of PINK1 in the mitochondrial matrix.
by: Ruth E Thomas, et al.
Published: (2014-01-01)

PINK1/Parkin Mediated Mitophagy, Ca<sup>2+</sup> Signalling, and ER–Mitochondria Contacts in Parkinson’s Disease
by: Lucia Barazzuol, et al.
Published: (2020-03-01)

Drosophila PINK1 and parkin loss-of-function mutants display a range of non-motor Parkinson's disease phenotypes
by: Hannah Julienne, et al.
Published: (2017-08-01)

Hexokinases link DJ-1 to the PINK1/parkin pathway
by: David N. Hauser, et al.
Published: (2017-09-01)

The Michael J. Fox Foundation for Parkinson’s Research Strategy to Advance Therapeutic Development of PINK1 and Parkin
by: Shalini Padmanabhan, et al.
Published: (2019-07-01)

Stress-Induced Mitochondrial DJ-1: Role of Parkin, Pink1 and VDAC1
by: Hewitt, Sarah
Published: (2016)

PINK1 is selectively stabilized on impaired mitochondria to activate Parkin.
by: Derek P Narendra, et al.
Published: (2010-01-01)

PINK1 and Parkin complementarily protect dopaminergic neurons in vertebrates
by: Roberto Gavinio
Published: (2014)

Parkinson’s disease–associated VPS35 mutant reduces mitochondrial membrane potential and impairs PINK1/Parkin-mediated mitophagy
by: Kai Yu Ma, et al.
Published: (2021-06-01)

Regulatory Roles of PINK1-Parkin and AMPK in Ubiquitin-Dependent Skeletal Muscle Mitophagy
by: Alex P. Seabright, et al.
Published: (2020-12-01)

Deficiency of parkin and PINK1 impairs age-dependent mitophagy in Drosophila
by: Tom Cornelissen, et al.
Published: (2018-05-01)

Temporal integration of mitochondrial stress signals by the PINK1:Parkin pathway
by: J. Logan Bowling, et al.
Published: (2019-08-01)

Mutations in PINK1 and Parkin impair ubiquitination of Mitofusins in human fibroblasts.
by: Aleksandar Rakovic, et al.
Published: (2011-03-01)

Phosphorylation of mitochondrial polyubiquitin by PINK1 promotes Parkin mitochondrial tethering.
by: Kahori Shiba-Fukushima, et al.
Published: (2014-12-01)

PINK1/Parkin-Mediated Mitophagy Promotes Resistance to Sonodynamic Therapy
by: Lin Song, et al.
Published: (2018-09-01)

Regulation of the Parkin E3 ligase by PINK1-dependent phosphorylation
by: Kazlauskaite, Agne
Published: (2015)

Structure and function of parkin, PINK1 and DJ-1, the three musketeers of neuroprotection
by: Jean-Francois eTrempe, et al.
Published: (2013-04-01)

Clueless, a protein required for mitochondrial function, interacts with the PINK1-Parkin complex in Drosophila
by: Aditya Sen, et al.
Published: (2015-06-01)

Salidroside Protects Dopaminergic Neurons by Enhancing PINK1/Parkin-Mediated Mitophagy
by: Ruru Li, et al.
Published: (2019-01-01)

PINK1 Is Dispensable for Mitochondrial Recruitment of Parkin and Activation of Mitophagy in Cardiac Myocytes.
by: Dieter A Kubli, et al.
Published: (2015-01-01)

PINK1 Primes Parkin-Mediated Ubiquitination of PARIS in Dopaminergic Neuronal Survival
by: Yunjong Lee, et al.
Published: (2017-01-01)

PINK1/Parkin-mediated mitophagy in mechanical ventilation-induced diaphragmatic dysfunction
by: Hui Yong, et al.
Published: (2021-08-01)

The mitochondrial processing peptidase regulates PINK1 processing, import, and Parkin recruitment
by: Greene, Andrew
Published: (2012)

Differential mitochondrial roles for α-synuclein in DRP1-dependent fission and PINK1/Parkin-mediated oxidation
by: Thomas J. Krzystek, et al.
Published: (2021-08-01)

Identification of parkin interactions: implications for Parkinson’s disease
by: Haylett, William Lloyd
Published: (2015)

Análisis de mutaciones en los genes PINK1 Y PARKIN en pacientes colombianos con enfermedad de Parkinson
by: Carolina Andrea Infante Molina, et al.
Published: (2014-07-01)

Paraquat Exposure Induces Pulmonary Cell Mitophagy by Enhancing the PINK1/Parkin Signaling
by: Kaixiang Liu, et al.
Published: (2020-01-01)