Apical Periodontitis - Is It Accountable for Cardiovascular Diseases?
The aim of this review was to assess the relationship between apical periodontitis and cardiovascular diseases and the predictive factors regarding this association. Cross sectional and observational studies have been included, which are mostly retrospective. A comprehensive search was performed i...
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doaj-5950054368164002bb6878cab476e72e2020-11-25T03:12:10ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2016-08-01108ZE08ZE1210.7860/JCDR/2016/19863.8253Apical Periodontitis - Is It Accountable for Cardiovascular Diseases? Paridhi Garg0Chandrakar Chaman1Senior Lecturer, Department of Consevative Dentistry and Endodontics, Inderprastha Dental College and Hospital, Sahibabad, Uttar Pradesh, India.Reader, Department of Consevative Dentistry and Endodontics, Kothiwal Dental College and Research Centre, Moradabad, Uttar Pradesh. India.The aim of this review was to assess the relationship between apical periodontitis and cardiovascular diseases and the predictive factors regarding this association. Cross sectional and observational studies have been included, which are mostly retrospective. A comprehensive search was performed in the Systematic Electronic Databases, PUBMED and MEDLINE from 1919 till September 2014. Articles were also hand searched. From 86 studies identified, all were read and 58 articles which were relevant were included in the text. Some articles were excluded because they were pertaining to periodontology and other systemic disorders. Some were solely animal studies and were thus excluded. Our results suggest an independent association between cardiovascular diseases and apical periodontitis. A causal relationship could not be established since weak parameters of risk have been assessed in the studies, population taken is difficult to compare and other confounding factors have not been ruled out. Only a more focused and better instituted scientific research can determine this association. Establishing a cause and effect relationship between apical periodontitis and cardiovascular diseases can affect the course of treatment of cardiovascular diseases. It is not only of interest from the scientific point of view but also from public health perspective.https://jcdr.net/articles/PDF/8253/19863_CE(EK)_F(AK)_PF1(ACAK)_PFA(AK)_PF2(PAG).pdfbacteraemiainflammationinterleukinsroot canal treatment |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Paridhi Garg Chandrakar Chaman |
spellingShingle |
Paridhi Garg Chandrakar Chaman Apical Periodontitis - Is It Accountable for Cardiovascular Diseases? Journal of Clinical and Diagnostic Research bacteraemia inflammation interleukins root canal treatment |
author_facet |
Paridhi Garg Chandrakar Chaman |
author_sort |
Paridhi Garg |
title |
Apical Periodontitis - Is It Accountable for Cardiovascular Diseases? |
title_short |
Apical Periodontitis - Is It Accountable for Cardiovascular Diseases? |
title_full |
Apical Periodontitis - Is It Accountable for Cardiovascular Diseases? |
title_fullStr |
Apical Periodontitis - Is It Accountable for Cardiovascular Diseases? |
title_full_unstemmed |
Apical Periodontitis - Is It Accountable for Cardiovascular Diseases? |
title_sort |
apical periodontitis - is it accountable for cardiovascular diseases? |
publisher |
JCDR Research and Publications Private Limited |
series |
Journal of Clinical and Diagnostic Research |
issn |
2249-782X 0973-709X |
publishDate |
2016-08-01 |
description |
The aim of this review was to assess the relationship between apical periodontitis and cardiovascular diseases and the predictive
factors regarding this association. Cross sectional and observational studies have been included, which are mostly retrospective. A
comprehensive search was performed in the Systematic Electronic Databases, PUBMED and MEDLINE from 1919 till September 2014.
Articles were also hand searched. From 86 studies identified, all were read and 58 articles which were relevant were included in the
text. Some articles were excluded because they were pertaining to periodontology and other systemic disorders. Some were solely
animal studies and were thus excluded. Our results suggest an independent association between cardiovascular diseases and apical
periodontitis. A causal relationship could not be established since weak parameters of risk have been assessed in the studies, population
taken is difficult to compare and other confounding factors have not been ruled out. Only a more focused and better instituted scientific
research can determine this association. Establishing a cause and effect relationship between apical periodontitis and cardiovascular
diseases can affect the course of treatment of cardiovascular diseases. It is not only of interest from the scientific point of view but also
from public health perspective. |
topic |
bacteraemia inflammation interleukins root canal treatment |
url |
https://jcdr.net/articles/PDF/8253/19863_CE(EK)_F(AK)_PF1(ACAK)_PFA(AK)_PF2(PAG).pdf |
work_keys_str_mv |
AT paridhigarg apicalperiodontitisisitaccountableforcardiovasculardiseases AT chandrakarchaman apicalperiodontitisisitaccountableforcardiovasculardiseases |
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