Modern technologies and algorithms for scaffolding assembled genomes.
The computational reconstruction of genome sequences from shotgun sequencing data has been greatly simplified by the advent of sequencing technologies that generate long reads. In the case of relatively small genomes (e.g., bacterial or viral), complete genome sequences can frequently be reconstruct...
Main Authors: | Jay Ghurye, Mihai Pop |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-06-01
|
Series: | PLoS Computational Biology |
Online Access: | https://doi.org/10.1371/journal.pcbi.1006994 |
Similar Items
-
Scaffolding of long read assemblies using long range contact information
by: Jay Ghurye, et al.
Published: (2017-07-01) -
MetaCarvel: linking assembly graph motifs to biological variants
by: Jay Ghurye, et al.
Published: (2019-08-01) -
Integrating Hi-C links with assembly graphs for chromosome-scale assembly.
by: Jay Ghurye, et al.
Published: (2019-08-01) -
What do Eulerian and Hamiltonian cycles have to do with genome assembly?
by: Paul Medvedev, et al.
Published: (2021-05-01) -
Assembly complexity of prokaryotic genomes using short reads
by: Pop Mihai, et al.
Published: (2010-01-01)