Transcriptome analysis and prognosis of ALDH isoforms in human cancer

Abstract Overexpression of ALDH is associated with cancer stem-like features and poor cancer prognosis. High ALDH activity has been observed in cancer stem-like cells. There are a total of 19 human ALDH isoforms, all of which are associated with reducing oxidative stress and protecting cells from da...

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Bibliographic Details
Main Authors: Peter Mu-Hsin Chang, Che-Hong Chen, Chi-Chun Yeh, Hsueh-Ju Lu, Tze-Tze Liu, Ming-Huang Chen, Chun-Yu Liu, Alexander T. H. Wu, Muh-Hwa Yang, Shyh-Kuan Tai, Daria Mochly-Rosen, Chi-Ying F. Huang
Format: Article
Language:English
Published: Nature Publishing Group 2018-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-21123-4