Results of the first Russian multicenter non-interventional study of Contour® TS glucometer

• Main Authors: Marina V. Shestakova, Liubov L. Bolotskaya, Mariia V. Verbovaia
• Format: Article
• Language: Russian
• Published: ZAO "Consilium Medicum" 2019-04-01
• Series: Consilium Medicum
• Subjects: non-interventional study; diabetes mellitus; insulin therapy; glucometer; glycaemic control
• Online Access: http://consilium.orscience.ru/en/archive/2019/vol-21-4-2019/results-of-the-first-russian-multicenter-non-interventional-study-of-contour-ts-glucometer_5458/?element

Aim. To evaluate fitness of Contour® TS glucometer (Contour® TS, Bayer/Ascensia*) – a system for blood glycemia level control, and its characteristics in everyday use for Russian patients with insulin dependent diabetes mellitus (DM) types 1 and 2 and endocrinologists. Study design. According to the inclusion criteria, 3759 patients were registered in the program, of which 3599 patients have completed the study as per 3 visits. The non-interventional study was conducted in 84 medical centers in RF during the period from October 2013 to June 2015. Age of insulin-dependent patients and patients on hypoglycaemic therapy was 18 years and older. Results. Observational program included – 1126 (31.29%) patients with type 1 diabetes mellitus and 2473 (68.71%) patients with type 2 diabetes mellitus. Following switch to Contour® TS, while insulin therapy regimens were maintained, it was noted that the rate of blood glucose measurement increased compared with Visit 1 (p<0.0001). Upon assessment of satisfaction with the device, virtually all questions were answered as “good” and “perfect” by more than 90% patients and 95% study doctors. Upon assessment of the quality of life by EQ-5D, increase of this parameter was noted in 6 months, at Visit 3 (p<0.0001). No glucometer-associated malfunction were registered during the study. Additional data from general clinical experience of each patient that allowed to establish significant reduction of the levels of glycosilated haemoglobin and pre-prandial blood glucose just in 3 months at Visit 2, significant reduction of reported hypoglycaemia episodes as calculated per one patient have been obtained during the study. Additional data on the prevalence of macro- and microvascular complications were obtained during the study, and the highest per cent was for non-proliferative retinopathy and nephropathy at the stage of albuminuria. The most common among concomitant diseases were arterial hypertension, dyslipidemia and coronary artery disease. Conclusion. Use of Contour® TS glucometer by the patients, while insulin therapy regimens were maintained, led to increase in the rate of blood glucose measurements by up to 4–6 times during the day and statistically significant improvement in blood glucose control.