Association between Fcγ receptor IIA, IIIA and IIIB genetic polymorphisms and susceptibility to severe malaria anemia in children in western Kenya
Abstract Background Naturally-acquired immunity to Plasmodium falciparum malaria develops after several episodes of infection. Fc gamma receptors (FcγRs) bind to immunoglobulin G (IgG) antibodies and mediate phagocytosis of opsonized microbes, thereby, linking humoral and cellular immunity. FcγR pol...
Main Authors: | Elly O. Munde, Winnie A. Okeyo, Evans Raballah, Samuel B. Anyona, Tom Were, John M. Ong’echa, Douglas J. Perkins, Collins Ouma |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-04-01
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Series: | BMC Infectious Diseases |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12879-017-2390-0 |
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