Ticagrelor Use in Stroke Patients: Past, Present, and Future
Rahul Chandra, Harneel Saini, Russell Cerejo, Ashis Tayal, Konark Malhotra Department of Neurology, Allegheny Health Network, Pittsburgh, PA, USACorrespondence: Konark MalhotraDepartment of Neurology, Allegheny Health Network, Pittsburgh, PA, USATel +1- 412-359-8841Fax +1- 412-442-2115Email konark.m...
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doaj-59ad355435c4465e82387e0e26fecda92021-06-20T19:51:19ZengDove Medical PressVascular Health and Risk Management1178-20482021-06-01Volume 1735736265865Ticagrelor Use in Stroke Patients: Past, Present, and FutureChandra RSaini HCerejo RTayal AMalhotra KRahul Chandra, Harneel Saini, Russell Cerejo, Ashis Tayal, Konark Malhotra Department of Neurology, Allegheny Health Network, Pittsburgh, PA, USACorrespondence: Konark MalhotraDepartment of Neurology, Allegheny Health Network, Pittsburgh, PA, USATel +1- 412-359-8841Fax +1- 412-442-2115Email konark.malhotra@yahoo.comAbstract: Antiplatelet medications are the mainstay for secondary stroke treatment. Aspirin, clopidogrel, and aspirin-dipyridamole are commonly used antiplatelet medications. Other antiplatelet medications such as ticagrelor and prasugrel have been majorly used in cardiovascular or neuro-interventional specialties. Recent studies have paved a way to their use in secondary stroke prevention. In this review, we have briefly discussed the pharmacology of ticagrelor, published literature in cardiology and stroke trials, use of ticagrelor among patients with ischemic strokes, and compared its efficacy, limitations and side-effects with other antiplatelet medications.Keywords: Ticagrelor, stroke, clopidogrel, platelet inhibitionhttps://www.dovepress.com/ticagrelor-use-in-stroke-patients-past-present-and-future-peer-reviewed-fulltext-article-VHRMticagrelorstrokeclopidogrelplatelet inhibition |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Chandra R Saini H Cerejo R Tayal A Malhotra K |
spellingShingle |
Chandra R Saini H Cerejo R Tayal A Malhotra K Ticagrelor Use in Stroke Patients: Past, Present, and Future Vascular Health and Risk Management ticagrelor stroke clopidogrel platelet inhibition |
author_facet |
Chandra R Saini H Cerejo R Tayal A Malhotra K |
author_sort |
Chandra R |
title |
Ticagrelor Use in Stroke Patients: Past, Present, and Future |
title_short |
Ticagrelor Use in Stroke Patients: Past, Present, and Future |
title_full |
Ticagrelor Use in Stroke Patients: Past, Present, and Future |
title_fullStr |
Ticagrelor Use in Stroke Patients: Past, Present, and Future |
title_full_unstemmed |
Ticagrelor Use in Stroke Patients: Past, Present, and Future |
title_sort |
ticagrelor use in stroke patients: past, present, and future |
publisher |
Dove Medical Press |
series |
Vascular Health and Risk Management |
issn |
1178-2048 |
publishDate |
2021-06-01 |
description |
Rahul Chandra, Harneel Saini, Russell Cerejo, Ashis Tayal, Konark Malhotra Department of Neurology, Allegheny Health Network, Pittsburgh, PA, USACorrespondence: Konark MalhotraDepartment of Neurology, Allegheny Health Network, Pittsburgh, PA, USATel +1- 412-359-8841Fax +1- 412-442-2115Email konark.malhotra@yahoo.comAbstract: Antiplatelet medications are the mainstay for secondary stroke treatment. Aspirin, clopidogrel, and aspirin-dipyridamole are commonly used antiplatelet medications. Other antiplatelet medications such as ticagrelor and prasugrel have been majorly used in cardiovascular or neuro-interventional specialties. Recent studies have paved a way to their use in secondary stroke prevention. In this review, we have briefly discussed the pharmacology of ticagrelor, published literature in cardiology and stroke trials, use of ticagrelor among patients with ischemic strokes, and compared its efficacy, limitations and side-effects with other antiplatelet medications.Keywords: Ticagrelor, stroke, clopidogrel, platelet inhibition |
topic |
ticagrelor stroke clopidogrel platelet inhibition |
url |
https://www.dovepress.com/ticagrelor-use-in-stroke-patients-past-present-and-future-peer-reviewed-fulltext-article-VHRM |
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