Synthesis, characterization and anti-fungal evaluation of Ni(II) and Cu(II) complexes with a derivative of 4-aminoantipyrine
Transition metal complexes of Ni(II) and Cu(II) metal ions with the general stoichiometry [M(L)X]X and [M(L)SO4], where M = Ni(II) and Cu(II), L = (1E)-N-((5-((E)-(2,3-dimethyl-1-phenyl-4-pyrazolineimino)methyl)thiophen-2-yl)methylene)-2,3-dimethyl-1-phenyl-4-pyrazolineamine and X = Cl−, NO3− and SO...
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doaj-59b81e5d420e4bcd8ef797c1e98c60d12020-11-24T21:36:21ZengTaylor & Francis GroupJournal of Taibah University for Science1658-36552017-01-0111111012010.1016/j.jtusci.2015.11.003Synthesis, characterization and anti-fungal evaluation of Ni(II) and Cu(II) complexes with a derivative of 4-aminoantipyrineMonika Tyagi0Sulekh Chandra1Prateek Tyagi2Jameel Akhtar3Arvind Kandan4Baleswar Singh5Department of Chemistry, Zakir Husain Delhi College (University of Delhi), JLN-Marg, New Delhi 110 002, IndiaDepartment of Chemistry, Zakir Husain Delhi College (University of Delhi), JLN-Marg, New Delhi 110 002, IndiaDepartment of Chemistry, Zakir Husain Delhi College (University of Delhi), JLN-Marg, New Delhi 110 002, IndiaDivision of Plant Quarantine, National Bureau of Plant Genetic Resources, Pusa Campus, New Delhi 110 002, IndiaDivision of Plant Quarantine, National Bureau of Plant Genetic Resources, Pusa Campus, New Delhi 110 002, IndiaDivision of Plant Quarantine, National Bureau of Plant Genetic Resources, Pusa Campus, New Delhi 110 002, IndiaTransition metal complexes of Ni(II) and Cu(II) metal ions with the general stoichiometry [M(L)X]X and [M(L)SO4], where M = Ni(II) and Cu(II), L = (1E)-N-((5-((E)-(2,3-dimethyl-1-phenyl-4-pyrazolineimino)methyl)thiophen-2-yl)methylene)-2,3-dimethyl-1-phenyl-4-pyrazolineamine and X = Cl−, NO3− and SO42−, have been synthesized and characterized. The synthesized ligand and metal complexes were characterized by 1H NMR, IR, mass spectrometry, UV–Vis spectra and EPR. In molecular modelling, the geometries of the Schiff's base and metal complexes were fully optimized with respect to the energy using the 6-31g(d,p) basis set. The nickel(II) complexes were found to have octahedral geometry, whereas the copper(II) complexes were of tetragonal geometry. The covalency factor (β) and orbital reduction factor (k) suggest the covalent nature of the complexes. To develop broad spectrum new molecules against seed-borne fungi, the minimum inhibitory concentration (MIC) of the ligand and its metal complexes was evaluated by the serial dilution method.http://www.sciencedirect.com/science/article/pii/S1658365515001788Schiff's base complexesSpectroscopicMolecular modellingAnti-fungal activity |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Monika Tyagi Sulekh Chandra Prateek Tyagi Jameel Akhtar Arvind Kandan Baleswar Singh |
spellingShingle |
Monika Tyagi Sulekh Chandra Prateek Tyagi Jameel Akhtar Arvind Kandan Baleswar Singh Synthesis, characterization and anti-fungal evaluation of Ni(II) and Cu(II) complexes with a derivative of 4-aminoantipyrine Journal of Taibah University for Science Schiff's base complexes Spectroscopic Molecular modelling Anti-fungal activity |
author_facet |
Monika Tyagi Sulekh Chandra Prateek Tyagi Jameel Akhtar Arvind Kandan Baleswar Singh |
author_sort |
Monika Tyagi |
title |
Synthesis, characterization and anti-fungal evaluation of Ni(II) and Cu(II) complexes with a derivative of 4-aminoantipyrine |
title_short |
Synthesis, characterization and anti-fungal evaluation of Ni(II) and Cu(II) complexes with a derivative of 4-aminoantipyrine |
title_full |
Synthesis, characterization and anti-fungal evaluation of Ni(II) and Cu(II) complexes with a derivative of 4-aminoantipyrine |
title_fullStr |
Synthesis, characterization and anti-fungal evaluation of Ni(II) and Cu(II) complexes with a derivative of 4-aminoantipyrine |
title_full_unstemmed |
Synthesis, characterization and anti-fungal evaluation of Ni(II) and Cu(II) complexes with a derivative of 4-aminoantipyrine |
title_sort |
synthesis, characterization and anti-fungal evaluation of ni(ii) and cu(ii) complexes with a derivative of 4-aminoantipyrine |
publisher |
Taylor & Francis Group |
series |
Journal of Taibah University for Science |
issn |
1658-3655 |
publishDate |
2017-01-01 |
description |
Transition metal complexes of Ni(II) and Cu(II) metal ions with the general stoichiometry [M(L)X]X and [M(L)SO4], where M = Ni(II) and Cu(II), L = (1E)-N-((5-((E)-(2,3-dimethyl-1-phenyl-4-pyrazolineimino)methyl)thiophen-2-yl)methylene)-2,3-dimethyl-1-phenyl-4-pyrazolineamine and X = Cl−, NO3− and SO42−, have been synthesized and characterized. The synthesized ligand and metal complexes were characterized by 1H NMR, IR, mass spectrometry, UV–Vis spectra and EPR. In molecular modelling, the geometries of the Schiff's base and metal complexes were fully optimized with respect to the energy using the 6-31g(d,p) basis set. The nickel(II) complexes were found to have octahedral geometry, whereas the copper(II) complexes were of tetragonal geometry. The covalency factor (β) and orbital reduction factor (k) suggest the covalent nature of the complexes. To develop broad spectrum new molecules against seed-borne fungi, the minimum inhibitory concentration (MIC) of the ligand and its metal complexes was evaluated by the serial dilution method. |
topic |
Schiff's base complexes Spectroscopic Molecular modelling Anti-fungal activity |
url |
http://www.sciencedirect.com/science/article/pii/S1658365515001788 |
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