Mechanical unloading enhances bone destruction and tumor expansion in multiple myeloma: Critical roles of osteocytic RANKL induction

Mechanical unloading enhances bone destruction and tumor expansion in multiple myeloma: Critical roles of osteocytic RANKL induction

Bibliographic Details
Main Authors: Kotaro Tanimoto, Masahiro Hiasa, Hirofumi Tenshin, Jumpei Teramachi, Asuka Oda, Takeshi Harada, Mohannad Ashter, Kimiko Sogabe, Masahiro Oura, Itsuro Endo, Toshio Matsumoto, Eiji Tanaka, Masahiro Abe
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Bone Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2352187220301856
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spelling doaj-59bb656d11b94812a125e0d04fe6fcd02020-11-25T04:01:44ZengElsevierBone Reports2352-18722020-10-0113100425Mechanical unloading enhances bone destruction and tumor expansion in multiple myeloma: Critical roles of osteocytic RANKL inductionKotaro Tanimoto0Masahiro Hiasa1Hirofumi Tenshin2Jumpei Teramachi3Asuka Oda4Takeshi Harada5Mohannad Ashter6Kimiko Sogabe7Masahiro Oura8Itsuro Endo9Toshio Matsumoto10Eiji Tanaka11Masahiro Abe12Department of Orthodontics and Dentofacial Orthopedic, Tokushima University, Tokushima, Japan, Tokushima, Japan; Department of Hematology, Endocrinology and Metabolism, Tokushima University, Tokushima, Japan, Tokushim, Japan; Corresponding author at: Department of Orthodontics and Dentofacial Orthopedic, Tokushima University, Tokushima, Japan, Tokushima, Japan.Department of Orthodontics and Dentofacial Orthopedic, Tokushima University, Tokushima, Japan, Tokushima, Japan; Department of Hematology, Endocrinology and Metabolism, Tokushima University, Tokushima, Japan, Tokushim, JapanDepartment of Orthodontics and Dentofacial Orthopedic, Tokushima University, Tokushima, Japan, Tokushima, Japan; Department of Hematology, Endocrinology and Metabolism, Institute of Biomedical Sciences, Tokushima Univeersity, Tokushim, JapanDepartment of Hematology, Endocrinology and Metabolism, Tokushima University, Tokushima, Japan, Tokushim, Japan; Department of Tissue Regeneration, Tokushima University, Tokushima, Japan, Tokushima, JapanDepartment of Hematology, Endocrinology and Metabolism, Tokushima University, Tokushima, Japan, Tokushim, JapanDepartment of Hematology, Endocrinology and Metabolism, Tokushima University, Tokushima, Japan, Tokushim, JapanDepartment of Orthodontics and Dentofacial Orthopedic, Tokushima University, Tokushima, Japan, Tokushima, Japan; Department of Hematology, Endocrinology and Metabolism, Tokushima University, Tokushima, Japan, Tokushim, JapanDepartment of Hematology, Endocrinology and Metabolism, Tokushima University, Tokushima, Japan, Tokushim, JapanDepartment of Hematology, Endocrinology and Metabolism, Tokushima University, Tokushima, Japan, Tokushim, JapanDepartment of Hematology, Endocrinology and Metabolism, Tokushima University, Tokushima, Japan, Tokushim, JapanFujii Memorial Institute of Medical Sciences, Tokushima University, Tokushima, JapanDepartment of Orthodontics and Dentofacial Orthopedic, Tokushima University, Tokushima, Japan, Tokushima, JapanDepartment of Hematology, Endocrinology and Metabolism, Tokushima University, Tokushima, Japan, Tokushim, Japanhttp://www.sciencedirect.com/science/article/pii/S2352187220301856
collection DOAJ
language English
format Article
sources DOAJ
author Kotaro Tanimoto
Masahiro Hiasa
Hirofumi Tenshin
Jumpei Teramachi
Asuka Oda
Takeshi Harada
Mohannad Ashter
Kimiko Sogabe
Masahiro Oura
Itsuro Endo
Toshio Matsumoto
Eiji Tanaka
Masahiro Abe
spellingShingle Kotaro Tanimoto
Masahiro Hiasa
Hirofumi Tenshin
Jumpei Teramachi
Asuka Oda
Takeshi Harada
Mohannad Ashter
Kimiko Sogabe
Masahiro Oura
Itsuro Endo
Toshio Matsumoto
Eiji Tanaka
Masahiro Abe
Mechanical unloading enhances bone destruction and tumor expansion in multiple myeloma: Critical roles of osteocytic RANKL induction
Bone Reports
author_facet Kotaro Tanimoto
Masahiro Hiasa
Hirofumi Tenshin
Jumpei Teramachi
Asuka Oda
Takeshi Harada
Mohannad Ashter
Kimiko Sogabe
Masahiro Oura
Itsuro Endo
Toshio Matsumoto
Eiji Tanaka
Masahiro Abe
author_sort Kotaro Tanimoto
title Mechanical unloading enhances bone destruction and tumor expansion in multiple myeloma: Critical roles of osteocytic RANKL induction
title_short Mechanical unloading enhances bone destruction and tumor expansion in multiple myeloma: Critical roles of osteocytic RANKL induction
title_full Mechanical unloading enhances bone destruction and tumor expansion in multiple myeloma: Critical roles of osteocytic RANKL induction
title_fullStr Mechanical unloading enhances bone destruction and tumor expansion in multiple myeloma: Critical roles of osteocytic RANKL induction
title_full_unstemmed Mechanical unloading enhances bone destruction and tumor expansion in multiple myeloma: Critical roles of osteocytic RANKL induction
title_sort mechanical unloading enhances bone destruction and tumor expansion in multiple myeloma: critical roles of osteocytic rankl induction
publisher Elsevier
series Bone Reports
issn 2352-1872
publishDate 2020-10-01
url http://www.sciencedirect.com/science/article/pii/S2352187220301856
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