Comparison of short- with long-term regeneration results after digital nerve reconstruction with muscle-in-vein conduits

• Main Authors: Jennifer Lynn Schiefer, Lukas Schulz, Rebekka Rath, Stéphane Stahl, Hans-Eberhard Schaller, Theodora Manoli
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2015-01-01
• Series: Neural Regeneration Research
• Subjects: peripheral nerve; regeneration; muscle-in-vein conduits; digital nerves; sensory recovery; Semmes-Weinstein; two-point discrimination; outcome; short-term; long-term
• Online Access: http://www.nrronline.org/article.asp?issn=1673-5374;year=2015;volume=10;issue=10;spage=1674;epage=1677;aulast=Schiefer
• ISSN: 1673-5374

Muscle-in-vein conduits are used alternatively to nerve grafts for bridging nerve defects. The purpose of this study was to examine short- and long-term regeneration results after digital nerve reconstruction with muscle-in-vein conduits. Static and moving two-point discriminations and Semmes-Weinstein Monofilaments were used to evaluate sensory recovery 6-12 months and 14-35 months after repair of digital nerves with muscle-in-vein in 7 cases. Both follow-ups were performed after clinical signs of progressing regeneration disappeared. In 4 of 7 cases, a further recovery of both two-point discriminations and in another case of only the static two-point discrimination of 1-3 mm could be found between the short-term and long-term follow-up examination. Moreover, a late recovery of both two-point discriminations was demonstrated in another case. Four of 7 cases showed a sensory improvement by one Semmes-Weinstein Monofilaments. This pilot study suggests that sensory recovery still takes place even when clinical signs of progressing regeneration disappear.