Exosome-mediated transfer of miR-93-5p from cancer-associated fibroblasts confer radioresistance in colorectal cancer cells by downregulating FOXA1 and upregulating TGFB3
Abstract Background Cancer-associated fibroblasts (CAFs) have been intensively studied in recent studies with aims of finding more concrete evidence on their mechanism of involvement in tumor progression, which is currently unknown. CAFs can secrete exosomes which are loaded with proteins, lipids an...
Main Authors: | Xijuan Chen, Junqi Liu, Qinglan Zhang, Baoxing Liu, Yan Cheng, Yonglei Zhang, Yanan Sun, Hong Ge, Yingqiang Liu |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-04-01
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Series: | Journal of Experimental & Clinical Cancer Research |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13046-019-1507-2 |
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