Ghrelin and vascular protection

Ghrelin and vascular protection

Ghrelin is a small peptide with important roles in the regulation of appetite, gut motility, glucose homeostasis as well as cardiovascular protection. This review highlights the role that acyl ghrelin plays in maintaining normal endothelial function by maintaining the balance of vasodilator-vasocons...

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Bibliographic Details
Main Authors: James T Pearson, Mikiyasu Shirai, Vijayakumar Sukumaran, Cheng-Kun Du, Hirotsugu Tsuchimochi, Takashi Sonobe, Mark T Waddingham, Rajesh Katare, Daryl O Schwenke
Format: Article
Language:English
Published: Bioscientifica 2019-09-01
Series:Vascular Biology
Subjects:
ghrelin
ghs-r1a
vasodilation
angiogenesis
inflammation
Online Access:https://vb.bioscientifica.com/view/journals/vb/1/1/VB-19-0024.xml
Description
Summary:Ghrelin is a small peptide with important roles in the regulation of appetite, gut motility, glucose homeostasis as well as cardiovascular protection. This review highlights the role that acyl ghrelin plays in maintaining normal endothelial function by maintaining the balance of vasodilator-vasoconstrictor factors, inhibiting inflammatory cytokine production and immune cell recruitment to sites of vascular injury and by promoting angiogenesis.
ISSN:2516-5658
2516-5658

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