Ghrelin and vascular protection

Ghrelin and vascular protection

Ghrelin is a small peptide with important roles in the regulation of appetite, gut motility, glucose homeostasis as well as cardiovascular protection. This review highlights the role that acyl ghrelin plays in maintaining normal endothelial function by maintaining the balance of vasodilator-vasocons...

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Main Authors: James T Pearson, Mikiyasu Shirai, Vijayakumar Sukumaran, Cheng-Kun Du, Hirotsugu Tsuchimochi, Takashi Sonobe, Mark T Waddingham, Rajesh Katare, Daryl O Schwenke
Format: Article
Language:English
Published: Bioscientifica 2019-09-01
Series:Vascular Biology
Subjects:
ghrelin
ghs-r1a
vasodilation
angiogenesis
inflammation
Online Access:https://vb.bioscientifica.com/view/journals/vb/1/1/VB-19-0024.xml
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spelling doaj-5a0dbb4f12df4203bf8e2a9d84c7af1a2020-11-25T02:47:37ZengBioscientificaVascular Biology2516-56582516-56582019-09-0111H97H102https://doi.org/10.1530/VB-19-0024Ghrelin and vascular protectionJames T Pearson0Mikiyasu Shirai1Vijayakumar Sukumaran2Cheng-Kun Du3Hirotsugu Tsuchimochi4Takashi Sonobe5Mark T Waddingham6Rajesh Katare7Daryl O Schwenke8Department of Cardiac Physiology, National Cerebral and Cardiovascular Center Research Institute, Osaka, Japan; Department of Physiology and Monash Biomedicine Discovery Institute, Monash University, Clayton, Victoria, AustraliaDepartment of Cardiac Physiology, National Cerebral and Cardiovascular Center Research Institute, Osaka, JapanDepartment of Cardiac Physiology, National Cerebral and Cardiovascular Center Research Institute, Osaka, JapanDepartment of Cardiac Physiology, National Cerebral and Cardiovascular Center Research Institute, Osaka, JapanDepartment of Cardiac Physiology, National Cerebral and Cardiovascular Center Research Institute, Osaka, JapanDepartment of Cardiac Physiology, National Cerebral and Cardiovascular Center Research Institute, Osaka, JapanDepartment of Cardiac Physiology, National Cerebral and Cardiovascular Center Research Institute, Osaka, JapanDepartment of Physiology, HeartOtago, School of Biomedical Sciences University of Otago, Dunedin, New ZealandDepartment of Physiology, HeartOtago, School of Biomedical Sciences University of Otago, Dunedin, New ZealandGhrelin is a small peptide with important roles in the regulation of appetite, gut motility, glucose homeostasis as well as cardiovascular protection. This review highlights the role that acyl ghrelin plays in maintaining normal endothelial function by maintaining the balance of vasodilator-vasoconstrictor factors, inhibiting inflammatory cytokine production and immune cell recruitment to sites of vascular injury and by promoting angiogenesis.https://vb.bioscientifica.com/view/journals/vb/1/1/VB-19-0024.xmlghrelinghs-r1avasodilationangiogenesisinflammation
collection DOAJ
language English
format Article
sources DOAJ
author James T Pearson
Mikiyasu Shirai
Vijayakumar Sukumaran
Cheng-Kun Du
Hirotsugu Tsuchimochi
Takashi Sonobe
Mark T Waddingham
Rajesh Katare
Daryl O Schwenke
spellingShingle James T Pearson
Mikiyasu Shirai
Vijayakumar Sukumaran
Cheng-Kun Du
Hirotsugu Tsuchimochi
Takashi Sonobe
Mark T Waddingham
Rajesh Katare
Daryl O Schwenke
Ghrelin and vascular protection
Vascular Biology
ghrelin
ghs-r1a
vasodilation
angiogenesis
inflammation
author_facet James T Pearson
Mikiyasu Shirai
Vijayakumar Sukumaran
Cheng-Kun Du
Hirotsugu Tsuchimochi
Takashi Sonobe
Mark T Waddingham
Rajesh Katare
Daryl O Schwenke
author_sort James T Pearson
title Ghrelin and vascular protection
title_short Ghrelin and vascular protection
title_full Ghrelin and vascular protection
title_fullStr Ghrelin and vascular protection
title_full_unstemmed Ghrelin and vascular protection
title_sort ghrelin and vascular protection
publisher Bioscientifica
series Vascular Biology
issn 2516-5658
2516-5658
publishDate 2019-09-01
description Ghrelin is a small peptide with important roles in the regulation of appetite, gut motility, glucose homeostasis as well as cardiovascular protection. This review highlights the role that acyl ghrelin plays in maintaining normal endothelial function by maintaining the balance of vasodilator-vasoconstrictor factors, inhibiting inflammatory cytokine production and immune cell recruitment to sites of vascular injury and by promoting angiogenesis.
topic ghrelin
ghs-r1a
vasodilation
angiogenesis
inflammation
url https://vb.bioscientifica.com/view/journals/vb/1/1/VB-19-0024.xml
work_keys_str_mv AT jamestpearson ghrelinandvascularprotection
AT mikiyasushirai ghrelinandvascularprotection
AT vijayakumarsukumaran ghrelinandvascularprotection
AT chengkundu ghrelinandvascularprotection
AT hirotsugutsuchimochi ghrelinandvascularprotection
AT takashisonobe ghrelinandvascularprotection
AT marktwaddingham ghrelinandvascularprotection
AT rajeshkatare ghrelinandvascularprotection
AT daryloschwenke ghrelinandvascularprotection
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