IL-6 secretion in osteoarthritis patients is mediated by chondrocyte-synovial fibroblast cross-talk and is enhanced by obesity
Abstract Increasing evidence suggests that inflammation plays a central role in driving joint pathology in certain patients with osteoarthritis (OA). Since many patients with OA are obese and increased adiposity is associated with chronic inflammation, we investigated whether obese patients with hip...
Main Authors: | Mark J. Pearson, Dietmar Herndler-Brandstetter, Mohammad A. Tariq, Thomas A. Nicholson, Ashleigh M. Philp, Hannah L. Smith, Edward T. Davis, Simon W. Jones, Janet M. Lord |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-06-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-017-03759-w |
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