Functional antibodies against Plasmodium falciparum sporozoites are associated with a longer time to qPCR-detected infection among schoolchildren in Burkina Faso [version 1; referees: 1 approved, 2 approved with reservations]

Functional antibodies against Plasmodium falciparum sporozoites are associated with a longer time to qPCR-detected infection among schoolchildren in Burkina Faso [version 1; referees: 1 approved, 2 approved with reservations]

Background: Individuals living in malaria-endemic regions develop naturally acquired immunity against severe malarial disease, but it is unclear whether immunity that affects the establishment of infections develops following continuous natural exposure. Methods: We cleared schoolchildren in Burkina...

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Main Authors: Aissata Barry, Marije C. Behet, Issa Nébié, Kjerstin Lanke, Lynn Grignard, Alphonse Ouedraogo, Issiaka Soulama, Chris Drakeley, Robert Sauerwein, Judith M. Bolscher, Koen J. Dechering, Teun Bousema, Alfred B. Tiono, Bronner P. Gonçalves
Format: Article
Language:English
Published: Wellcome 2018-12-01
Series:Wellcome Open Research
Online Access:https://wellcomeopenresearch.org/articles/3-159/v1

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