Dynamic changes of CSF sTREM2 in preclinical Alzheimer’s disease: the CABLE study

Dynamic changes of CSF sTREM2 in preclinical Alzheimer’s disease: the CABLE study

Abstract Background Loss of function of triggering receptor expressed on myeloid cell 2 (TREM2), a key receptor selectively expressed by microglia in the brain, contributes to the development of Alzheimer’s disease (AD). Whether TREM2 levels are pathologically altered during the preclinical phase, a...

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Bibliographic Details
Main Authors: Ling-Zhi Ma, Lan Tan, Yan-Lin Bi, Xue-Ning Shen, Wei Xu, Ya-Hui Ma, Hong-Qi Li, Qiang Dong, Jin-Tai Yu
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Molecular Neurodegeneration
Subjects:
Alzheimer’s disease
sTREM2
Inflammation
Biomarkers
Neurodegeneration
Online Access:http://link.springer.com/article/10.1186/s13024-020-00374-8

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