Acetylcholine chloride 1% usage for intraoperative cataract surgery miosis

• Main Authors: Fernando Macei Drudi, Camila Lima, Lincoln Freitas, Milton Yogi, Heloisa Nascimento, Rubens Belfort Junior
• Format: Article
• Language: English
• Published: Sociedade Brasileira de Oftalmologia
• Series: Revista Brasileira de Oftalmologia
• Subjects: Acetilcolina/administração & dosagem; Agonistas colinérgicos/administração & dosagem; Facoemulsificação; Extração de catarata; Miose
• Online Access: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-72802017000500247&lng=en&tlng=en

Abstract Objective: To test the efficacy of Acetylcholine chloride use in obtaining intraoperative miosis on phacoemulsification cataract surgery. Methods: Patients with cataract diagnosis and elected for surgical phacoemulsification procedure were selected. All patients underwent conventional phacoemulsification procedure performed by a single surgeon and all patients had 0.2 ml of Acetylcholine chloride 1% irrigated in the anterior chamber at the end of the surgery. The pupillary diameter was measured immediately before the beginning of surgery, immediately before and two minutes after the use of acetylcholine chloride 1%. Results: A total of 30 eyes from 30 patients were included in the study. 18 were female, and mean age was of 69.5 years with a 7.2y standard deviation on the population study. The mean pupillary diameter immediately before the beginning of surgery was 7.5 mm with a standard deviation of 0.56 mm; the mean pupillary diameter immediately before the acetylcholine chloride 1% use (after the intraocular lens im-plantation) was 7.1 mm with a standard deviation of 0.57 mm. The mean pupillary diameter two minutes after the use of acetylcholine chloride 1% in the anterior chamber was 3.4 mm with standard deviation of 0.66 mm. The mean maximum action time of ACH chloride 1% was 64 seconds, with a standard deviation of 8 seconds. The mean intraocular pressure on the first postoperative day was 19.1 mmHg with a standard deviation of 2.45 mmHg. Conclusion: We conclude that acetylcholine chloride 1% is an important drug to obtaining intraoperative miosis in cataract surgery.