A potent anti‐dengue human antibody preferentially recognizes the conformation of E protein monomers assembled on the virus surface
Abstract Dengue virus (DENV), which consists of four serotypes (DENV1‐4), infects over 400 million people annually. Previous studies have indicated most human monoclonal antibodies (HMAbs) from dengue patients are cross‐reactive and poorly neutralizing. Rare neutralizing HMAbs are usually serotype‐s...
Main Authors: | Guntur Fibriansah, Joanne L Tan, Scott A Smith, Adamberage R deAlwis, Thiam‐Seng Ng, Victor A Kostyuchenko, Kristie D Ibarra, Jiaqi Wang, Eva Harris, Aravinda deSilva, James E Crowe Jr, Shee‐Mei Lok |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2014-03-01
|
Series: | EMBO Molecular Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1002/emmm.201303404 |
Similar Items
-
Atomic structure of the 26S proteasome lid reveals the mechanism of deubiquitinase inhibition
by: Corey M Dambacher, et al.
Published: (2016-01-01) -
Protein denaturation at the air-water interface and how to prevent it
by: Edoardo D'Imprima, et al.
Published: (2019-04-01) -
Structure-based membrane dome mechanism for Piezo mechanosensitivity
by: Yusong R Guo, et al.
Published: (2017-12-01) -
Abstract OR-9: Cryo-Electron Microscopy Studies of Flaviviruses
by: Victor A. Kostyuchenko, et al.
Published: (2019-06-01) -
A Workflow for Protein Structure Determination From Thin Crystal Lamella by Micro-Electron Diffraction
by: Emma V. Beale, et al.
Published: (2020-08-01)