5-Aminosalicylic Acid Loaded Chitosan-Carrageenan Hydrogel Beads with Potential Application for the Treatment of Inflammatory Bowel Disease

5-Aminosalicylic Acid Loaded Chitosan-Carrageenan Hydrogel Beads with Potential Application for the Treatment of Inflammatory Bowel Disease

The aim of our work is to prepare mucoadhesive particles with biopolymers and 5-Aminosalicylic acid (5ASA) using the ionotropic gelation technique to ensure a controlled drug release at the colon level with potential applications in the treatment of intestinal bowel disease (IBD). The preparation of...

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Bibliographic Details
Main Authors: Cristina Elena Stavarache, Adi Ghebaur, Sorina Dinescu, Iuliana Samoilă, Eugeniu Vasile, George Mihail Vlasceanu, Horia Iovu, Sorina Alexandra Gârea
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Polymers
Subjects:
chitosan
k-carrageenan
5-aminosalicylic acid
ionic gelation technique
drug delivery system
Online Access:https://www.mdpi.com/2073-4360/13/15/2463

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