Changes in inflammatory processes associated with selective vulnerability following mild impairment of oxidative metabolism
Abnormalities in oxidative metabolism and reductions of thiamine-dependent enzymes accompany many age-related neurodegenerative diseases. Thiamine deficiency (TD) produces a cascade of events including mild impairment of oxidative metabolism, activation of microglia, astrocytes and endothelial cells...
Main Authors: | Saravanan S. Karuppagounder, Qingli Shi, Hui Xu, Gary E. Gibson |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2007-05-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996107000174 |
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