Application of Citicoline in Neurological Disorders: A Systematic Review
Citicoline is a chemical compound involved in the synthesis of cell membranes. It also has other, not yet explained functions. Research on the use of citicoline is conducted in neurology, ophthalmology, and psychiatry. Citicoline is widely available as a dietary supplement. It is often used to enhan...
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doaj-5a6fb72aeb144cb6ae8ca6767e1a15102020-11-25T04:00:22ZengMDPI AGNutrients2072-66432020-10-01123113311310.3390/nu12103113Application of Citicoline in Neurological Disorders: A Systematic ReviewPatryk Jasielski0Faustyna Piędel1Mikołaj Piwek2Agata Rocka3Véronique Petit4Konrad Rejdak5Department of Neurology, Medical University of Lublin, 20-059 Lublin, PolandDepartment of Neurology, Medical University of Lublin, 20-059 Lublin, PolandDepartment of Neurology, Medical University of Lublin, 20-059 Lublin, PolandDepartment of Neurology, Medical University of Lublin, 20-059 Lublin, PolandDepartment of Neurology, Medical University of Lublin, 20-059 Lublin, PolandDepartment of Neurology, Medical University of Lublin, 20-059 Lublin, PolandCiticoline is a chemical compound involved in the synthesis of cell membranes. It also has other, not yet explained functions. Research on the use of citicoline is conducted in neurology, ophthalmology, and psychiatry. Citicoline is widely available as a dietary supplement. It is often used to enhance cognitive functions. In our article, accessible databases were searched for articles regarding citicoline use in neurological diseases. This article has a systemic review form. After rejecting non-eligible reports, 47 remaining articles were reviewed. The review found that citicoline has been proven to be a useful compound in preventing dementia progression. It also enhances cognitive functions among healthy individuals and improves prognosis after stroke. In an animal model of nerve damage and neuropathy, citicoline stimulated regeneration and lessened pain. Among patients who underwent brain trauma, citicoline has an unclear clinical effect. Citicoline has a wide range of effects and could be an essential substance in the treatment of many neurological diseases. Its positive impact on learning and cognitive functions among the healthy population is also worth noting.https://www.mdpi.com/2072-6643/12/10/3113citicolineneurologysupplementationtreatment |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Patryk Jasielski Faustyna Piędel Mikołaj Piwek Agata Rocka Véronique Petit Konrad Rejdak |
spellingShingle |
Patryk Jasielski Faustyna Piędel Mikołaj Piwek Agata Rocka Véronique Petit Konrad Rejdak Application of Citicoline in Neurological Disorders: A Systematic Review Nutrients citicoline neurology supplementation treatment |
author_facet |
Patryk Jasielski Faustyna Piędel Mikołaj Piwek Agata Rocka Véronique Petit Konrad Rejdak |
author_sort |
Patryk Jasielski |
title |
Application of Citicoline in Neurological Disorders: A Systematic Review |
title_short |
Application of Citicoline in Neurological Disorders: A Systematic Review |
title_full |
Application of Citicoline in Neurological Disorders: A Systematic Review |
title_fullStr |
Application of Citicoline in Neurological Disorders: A Systematic Review |
title_full_unstemmed |
Application of Citicoline in Neurological Disorders: A Systematic Review |
title_sort |
application of citicoline in neurological disorders: a systematic review |
publisher |
MDPI AG |
series |
Nutrients |
issn |
2072-6643 |
publishDate |
2020-10-01 |
description |
Citicoline is a chemical compound involved in the synthesis of cell membranes. It also has other, not yet explained functions. Research on the use of citicoline is conducted in neurology, ophthalmology, and psychiatry. Citicoline is widely available as a dietary supplement. It is often used to enhance cognitive functions. In our article, accessible databases were searched for articles regarding citicoline use in neurological diseases. This article has a systemic review form. After rejecting non-eligible reports, 47 remaining articles were reviewed. The review found that citicoline has been proven to be a useful compound in preventing dementia progression. It also enhances cognitive functions among healthy individuals and improves prognosis after stroke. In an animal model of nerve damage and neuropathy, citicoline stimulated regeneration and lessened pain. Among patients who underwent brain trauma, citicoline has an unclear clinical effect. Citicoline has a wide range of effects and could be an essential substance in the treatment of many neurological diseases. Its positive impact on learning and cognitive functions among the healthy population is also worth noting. |
topic |
citicoline neurology supplementation treatment |
url |
https://www.mdpi.com/2072-6643/12/10/3113 |
work_keys_str_mv |
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