Investigation of the mechanisms of VEGF-mediated compensatory lung growth: the role of the VEGF heparin-binding domain

Investigation of the mechanisms of VEGF-mediated compensatory lung growth: the role of the VEGF heparin-binding domain

Abstract Morbidity and mortality for neonates with congenital diaphragmatic hernia-associated pulmonary hypoplasia remains high. These patients may be deficient in vascular endothelial growth factor (VEGF). Our lab previously established that exogenous VEGF164 accelerates compensatory lung growth (C...

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Bibliographic Details
Main Authors: Lumeng J. Yu, Victoria H. Ko, Duy T. Dao, Jordan D. Secor, Amy Pan, Bennet S. Cho, Paul D. Mitchell, Hiroko Kishikawa, Diane R. Bielenberg, Mark Puder
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-91127-0

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