Arachidonic Acid and Docosahexaenoic Acid Metabolites in the Airways of Adults With Cystic Fibrosis: Effect of Docosahexaenoic Acid Supplementation

Arachidonic Acid and Docosahexaenoic Acid Metabolites in the Airways of Adults With Cystic Fibrosis: Effect of Docosahexaenoic Acid Supplementation

Cystic fibrosis (CF) is an autosomal recessive disorder, caused by genetic mutations in CF transmembrane conductance regulator protein. Several reports have indicated the presence of specific fatty acid alterations in CF patients, most notably decreased levels of plasmatic and tissue docosahexaenoic...

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Bibliographic Details
Main Authors: Elisabetta Teopompi, Patrizia Risé, Roberta Pisi, Carola Buccellati, Marina Aiello, Giovanna Pisi, Candida Tripodi, Valentina Fainardi, Enrico Clini, Alfredo Chetta, G. Enrico Rovati, Angelo Sala
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Pharmacology
Subjects:
15-lipoxygenase
sputum
inflammatory mediators
docosahexaenoic acid-DHA
arachidonic acid (AA or eicosatetraenoic acid)
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00938/full

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