CSF N-glycan profiles to investigate biomarkers in brain developmental disorders: application to leukodystrophies related to eIF2B mutations.

CSF N-glycan profiles to investigate biomarkers in brain developmental disorders: application to leukodystrophies related to eIF2B mutations.

BACKGROUND: Primary or secondary abnormalities of glycosylation have been reported in various brain diseases. Decreased asialotransferrin to sialotransferrin ratio in cerebrospinal fluid (CSF) is a diagnostic marker of leukodystrophies related to mutations of genes encoding translation initiation fa...

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Bibliographic Details
Main Authors: Anne Fogli, Christine Merle, Véronique Roussel, Raphael Schiffmann, Sylvie Ughetto, Manfred Theisen, Odile Boespflug-Tanguy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3430715?pdf=render

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http://europepmc.org/articles/PMC3430715?pdf=render

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