Effect of Danshu capsules combined with Xiyanping on acute cholecystitis treatment

• Main Authors: Hong-Liang Wang, Lv-Rong Yuan, Ya-Ming Liu
• Format: Article
• Language: English
• Published: Editorial Board of Journal of Hainan Medical University 2016-12-01
• Series: Journal of Hainan Medical University
• Subjects: Acute cholecystitis; Danshu capsules; Xiyanping; Combination therapy
• Online Access: http://www.hnykdxxb.com/PDF/201623/16.pdf

Objective: To observe the effect of Danshu capsules combined with Xiyanping on acute cholecystitis treatment and offer help to acute cholecystitis treatment. Methods: A total of 180 patients with acute cholecystitis were selected and randomly divided into groups: the observation group (90 people) and the control group (90 people). The patients in the control group were treated with conventional therapy and the patients in the observation group were treated with Danshu capsules combined with Xiyanping on the basis of conventional therapy. Immunological cell, cholecystitis related factors, inflammatory factors, and the coagulation function related factors were detected and analyzed before and after treatment. Results: Coagulation function related factors (PT and APTT), CD8+ , cholecystitis related factors (total bilirubin, amylase and PCT), inflammatory factor (hs-CRP, TNF-α, IL-6 and IL-10) in both groups after treatment significantly decreased. PA, immunological cell (CD3+ , CD4+ and CD4+ /CD8+ ) significantly increased compared with that before treatment (P<0.05). Changes of PP and FIB were not statistically significant (P>0.05). Coagulation function related factors (PT and APTT), CD8+ , cholecystitis related factors (total bilirubin, amylase and PCT), and inflammatory factor (hs-CRP, TNF-α, IL-6 and IL-10) in observation group after treatment decreased more significantly than that in control group (P<0.05). Conclusions: Danshu capsules combined with Xiyanping can perfect effectively immunological cell, cholecystitis related factors, inflammatory factors and coagulation function related factors on patients with acute cholecystitis, and it has important clinical significance for acute cholecystitis.