Non-invasive in vivo hyperspectral imaging of the retina for potential biomarker use in Alzheimer’s disease
The use of PET for detection of Aβ in the brain in AD has limitations; studies also indicate that retinal changes, including Aβ deposition, occur in AD. Here the authors demonstrate the potential to use in vivo retinal hyperspectral imaging as a surrogate for brain accumulation of Aβ.
Main Authors: | Xavier Hadoux, Flora Hui, Jeremiah K. H. Lim, Colin L. Masters, Alice Pébay, Sophie Chevalier, Jason Ha, Samantha Loi, Christopher J. Fowler, Christopher Rowe, Victor L. Villemagne, Edward N. Taylor, Christopher Fluke, Jean-Paul Soucy, Frédéric Lesage, Jean-Philippe Sylvestre, Pedro Rosa-Neto, Sulantha Mathotaarachchi, Serge Gauthier, Ziad S. Nasreddine, Jean Daniel Arbour, Marc-André Rhéaume, Sylvain Beaulieu, Mohamed Dirani, Christine T. O. Nguyen, Bang V. Bui, Robert Williamson, Jonathan G. Crowston, Peter van Wijngaarden |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2019-09-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-019-12242-1 |
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