Feasibility and Acceptability of a Healthy Nordic Diet Intervention for the Treatment of Depression: A Randomized Controlled Pilot Trial
Healthy diet interventions have been shown to improve depressive symptoms, but there is a need for randomized controlled trials (RCTs) that are double blind and investigate biological mechanisms. The primary objectives of this randomized controlled pilot trial were to test the palatability of the me...
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doaj-5b12ab35321d4261a4f36d98302446012021-03-11T00:06:06ZengMDPI AGNutrients2072-66432021-03-011390290210.3390/nu13030902Feasibility and Acceptability of a Healthy Nordic Diet Intervention for the Treatment of Depression: A Randomized Controlled Pilot TrialJulia A. Sabet0Moa S. Ekman1A. Sofia Lundvall2Ulf Risérus3Ulrica Johansson4Åsa Öström5Viola Adamsson6Yang Cao7Mussie Msghina8Robert J. Brummer9School of Medical Sciences, Faculty of Medicine and Health, Örebro University, Södra Grev Rosengatan 32, 70362 Örebro, SwedenSchool of Medical Sciences, Faculty of Medicine and Health, Örebro University, Södra Grev Rosengatan 32, 70362 Örebro, SwedenSchool of Medical Sciences, Faculty of Medicine and Health, Örebro University, Södra Grev Rosengatan 32, 70362 Örebro, SwedenDepartment of Public Health and Caring Sciences, Clinical Nutrition and Metabolism, Uppsala University, 75122 Uppsala, SwedenDepartment of Clinical Sciences, Paediatrics, Umeå University, 90185 Umeå, SwedenSchool of Hospitality, Culinary Arts and Meal Science, Örebro University, 71202 Grythyttan, SwedenDepartment of Public Health and Caring Sciences, Clinical Nutrition and Metabolism, Uppsala University, 75122 Uppsala, SwedenClinical Epidemiology and Biostatistics, School of Medical Sciences, Örebro University, 70182 Örebro, SwedenSchool of Medical Sciences, Faculty of Medicine and Health, Örebro University, Södra Grev Rosengatan 32, 70362 Örebro, SwedenSchool of Medical Sciences, Faculty of Medicine and Health, Örebro University, Södra Grev Rosengatan 32, 70362 Örebro, SwedenHealthy diet interventions have been shown to improve depressive symptoms, but there is a need for randomized controlled trials (RCTs) that are double blind and investigate biological mechanisms. The primary objectives of this randomized controlled pilot trial were to test the palatability of the meals and the acceptability of the intervention in preparation for an 8-week RCT in the future, which will investigate whether a healthy Nordic diet improves depressive symptoms in individuals with major depressive disorder, and associated biological mechanisms. Depressed (<i>n </i>=<i> </i>10) and non-depressed (<i>n </i>=<i> </i>6) women and men were randomized to receive either a healthy Nordic diet (ND) or a control diet (CD) for 8 days. Participants were blinded to their diet allocation and the study hypotheses. Health questionnaires were completed before and after the intervention and, throughout the study, questionnaires assessed participants’ liking for the meals, their sensory properties, adherence, and open-ended feedback. In the ND group, 75% of participants consumed only the provided foods, as instructed, compared to 50% of CD participants. The meals of both diets, on average, received good ratings for liking and sensory properties, though the ND ratings were somewhat higher. Overall, results were positive and informative, indicating that the planned RCT will be feasible and well-accepted, with some proposed modifications.https://www.mdpi.com/2072-6643/13/3/902depressionmajor depressive disorderdietnutritionrandomized controlled trialrandomized controlled pilot trial |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Julia A. Sabet Moa S. Ekman A. Sofia Lundvall Ulf Risérus Ulrica Johansson Åsa Öström Viola Adamsson Yang Cao Mussie Msghina Robert J. Brummer |
spellingShingle |
Julia A. Sabet Moa S. Ekman A. Sofia Lundvall Ulf Risérus Ulrica Johansson Åsa Öström Viola Adamsson Yang Cao Mussie Msghina Robert J. Brummer Feasibility and Acceptability of a Healthy Nordic Diet Intervention for the Treatment of Depression: A Randomized Controlled Pilot Trial Nutrients depression major depressive disorder diet nutrition randomized controlled trial randomized controlled pilot trial |
author_facet |
Julia A. Sabet Moa S. Ekman A. Sofia Lundvall Ulf Risérus Ulrica Johansson Åsa Öström Viola Adamsson Yang Cao Mussie Msghina Robert J. Brummer |
author_sort |
Julia A. Sabet |
title |
Feasibility and Acceptability of a Healthy Nordic Diet Intervention for the Treatment of Depression: A Randomized Controlled Pilot Trial |
title_short |
Feasibility and Acceptability of a Healthy Nordic Diet Intervention for the Treatment of Depression: A Randomized Controlled Pilot Trial |
title_full |
Feasibility and Acceptability of a Healthy Nordic Diet Intervention for the Treatment of Depression: A Randomized Controlled Pilot Trial |
title_fullStr |
Feasibility and Acceptability of a Healthy Nordic Diet Intervention for the Treatment of Depression: A Randomized Controlled Pilot Trial |
title_full_unstemmed |
Feasibility and Acceptability of a Healthy Nordic Diet Intervention for the Treatment of Depression: A Randomized Controlled Pilot Trial |
title_sort |
feasibility and acceptability of a healthy nordic diet intervention for the treatment of depression: a randomized controlled pilot trial |
publisher |
MDPI AG |
series |
Nutrients |
issn |
2072-6643 |
publishDate |
2021-03-01 |
description |
Healthy diet interventions have been shown to improve depressive symptoms, but there is a need for randomized controlled trials (RCTs) that are double blind and investigate biological mechanisms. The primary objectives of this randomized controlled pilot trial were to test the palatability of the meals and the acceptability of the intervention in preparation for an 8-week RCT in the future, which will investigate whether a healthy Nordic diet improves depressive symptoms in individuals with major depressive disorder, and associated biological mechanisms. Depressed (<i>n </i>=<i> </i>10) and non-depressed (<i>n </i>=<i> </i>6) women and men were randomized to receive either a healthy Nordic diet (ND) or a control diet (CD) for 8 days. Participants were blinded to their diet allocation and the study hypotheses. Health questionnaires were completed before and after the intervention and, throughout the study, questionnaires assessed participants’ liking for the meals, their sensory properties, adherence, and open-ended feedback. In the ND group, 75% of participants consumed only the provided foods, as instructed, compared to 50% of CD participants. The meals of both diets, on average, received good ratings for liking and sensory properties, though the ND ratings were somewhat higher. Overall, results were positive and informative, indicating that the planned RCT will be feasible and well-accepted, with some proposed modifications. |
topic |
depression major depressive disorder diet nutrition randomized controlled trial randomized controlled pilot trial |
url |
https://www.mdpi.com/2072-6643/13/3/902 |
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